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논문 기본 정보

자료유형
학술저널
저자정보
한도숙 (건국대학교 대학원 생물공학과 겸임교수) 김기숙 (건국대학교 대학원 생물공학과 겸임교수) 강상모 (건국대학교 생물공학과 교수)
저널정보
한국미용학회 한국미용학회지 한국미용학회지 제26권 제4호
발행연도
2020.1
수록면
886 - 896 (11page)

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초록· 키워드

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Spicules is a physical exfoliator that is known in academia that induces normal keratination cycles and further promotes skin metabolism and skin regeneration. In addition, based on the structural feature with its fine pores spicules, experimental attempts to use it as a percutaneous delivery system for cosmetics will be meaningful. To address this study has two-folded purposes: verifying the percutaneous absorbance of cosmetics manufactured by a combination of purified spicules and functional active ingredients, and identifying how much skin improvement the spicules-containing functional cosmetics through observe in those changes after applying to the actual skin. For these aims the percutaneous absorbance of niacinamide was evaluated on the artificial membrane similar to that of human skin was compared with the general functional cosmetics and the functional cosmetics containing 1% weight of purified spicules. In addition, clinical trial was conducted for four weeks targeting the total number of twenty women. As for the clinical trials experimental groups involves: a group with placebo cosmetics (C), general functional cosmetics (T1) and spicules-containing functional cosmetics (T2). As a result of the percutaneous absorption-testing of niacinamide showed that T2 significantly increased amount of absorptive & absorptivity of naiacinamide over time (p<.001). Furthermore, resulted in different changes on the skin, depending on their respective groups. In particular, the T2 has obtained the following statistically significant results: a decrease in eye bags laxity (p<.001), oral angle laxity (p<.001) and TEWL (p<.001), an increase in skin elasticity (p<<).001, skin density (p<.001) and skin brightness (p<.001). Thus, the purified spicules has been proven as material that helps absorb the active ingredients of cosmetics for improve aging skin.

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