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학술저널
저자정보
권혁성 (한양대학교) 김영서 (한양대학교) 이종민 (한양대학교 의과대학) 고성호 (한양대학교) 김현영 (한양대학교) 김철호 (한림대학교) 이승훈 (서울대학교병원) 정근화 (서울대학교) 김영대 (연세대학교) 권형민 (서울대학교) 김범준 (서울대학교) 김정민 (중앙대학교) 김범준 (울산대학교) 허성혁 (경희대학교) 장대일 (경희대학교)
저널정보
대한신경과학회 Journal of Clinical Neurology Journal of Clinical Neurology 제16권 제4호
발행연도
2020.1
수록면
605 - 611 (7page)

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Background and Purpose The incidence of ischemic stroke (IS) in young adults is increasing, and the associated large socioeconomic impact makes understanding IS in young adults important. We investigated the causes of and risk factors for IS in young adults, and their impact on outcomes. Methods The Stroke in Korean Young Adults (SKY) study is a standardized multicenter prospective study involving eight medical centers of the Republic of Korea. First-ever IS patients aged 18 years to 44 years were prospectively included in this study within 7 days of stroke onset. Their outcomes at 3 months were analyzed. Results This study enrolled 270 patients from April 2014 to December 2018, most (67.8%) of whom were male. About 41.5% of the patients had one or more vascular risk factors from among hypertension, diabetes mellitus, and dyslipidemia. However, only half of them had received regular treatment. Arterial dissection was more common in males, and systemic lupus erythematosus (SLE) and Moyamoya disease were more common in females. The outcome was favorable (modified Rankin Scale score of 0 or 1) in 81.9% of the patients at 3 months after stroke onset. More severe initial symptoms, higher initial glucose level, and SLE as a comorbidity were associated with unfavorable outcomes. Conclusions Young adult IS patients in Korea exhibit low awareness and poor management of their risk factors. Although the short-term outcome was relatively favorable in those patients, having SLE was associated with unfavorable outcomes. More attention needs to be paid for improving awareness and controlling risk factors in this population.

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