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논문 기본 정보

자료유형
학술저널
저자정보
Wang Sheng-Min (Department of Psychiatry Yeouido St. Mary’s Hospital College of Medicine The Catholic University of) Han Kyung-do (Department of Statistics and Actuarial Science Soongsil University) Kim Nak-Young (Department of Psychiatry Yeouido St. Mary’s Hospital College of Medicine The Catholic University of) Um Yoo Hyun (Department of Psychiatry St. Vincent Hospital College of Medicine The Catholic University of Korea) 강동우 (가톨릭대학교(성의교정)) Na Hae-Ran (Department of Psychiatry Yeouido St. Mary’s Hospital College of Medicine The Catholic University of) Lee Chang Uk (Department of Psychiatry Seoul St. Mary’s Hospital College of Medicine The Catholic University of K) Lim Hyun Kook (Department of Psychiatry Yeouido St. Mary’s Hospital College of Medicine The Catholic University of)
저널정보
대한신경정신의학회 PSYCHIATRY INVESTIGATION PSYCHIATRY INVESTIGATION 제17권 제10호
발행연도
2020.1
수록면
1,013 - 1,020 (8page)

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Objective Previous studies investigating association of alcohol intake and fracture risk in elderly yielded conflicting results. We first examined the association between alcohol intake and total fracture risk in elderly subjects and further analyzed whether the association varied by fracture locations.Methods This is a nationwide population-based cohort study which included all people aged 66 (n=1,431,539) receiving the National Screening Program during 2009?2014. Time-to-event were defined as duration from study recruitment, the day they received health screening, to the occurrence of fracture.Results Total fracture was significantly lower in mild drinkers [adjusted hazard ratio (aHR)=0.952; 95% confidence interval (95% CI) =0.931?0.973] and higher in heavy drinkers (aHR=1.246; 95% CI=1.201?1.294) than non-drinkers. Risk pattern of alcohol consumption and fracture differed according to affected bones. Similar J-shaped trends were observed for vertebra fractures, but risk of limb fracture showed a linear relationship with alcohol intake. For hip fracture, risk decrement was more pronounced in mild and moderate drinkers, and significant increment was noted only in very severe drinkers [≥60 g/day; (aHR)=1.446; 1.162?1.801].Conclusion Light to moderate drinking generally lowered risk of fractures, but association between alcohol and fracture risk varied depending on the affected bone lesions.

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