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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.1
- 수록면
- 68 - 72 (5page)
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초록· 키워드
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Hidradenitis suppurativa (HS) is a chronic recurrent inflammatory condition presenting with painful, deep-seated abscesses and sinus tracts in multifocal locations. Rarely, longstanding inflammation in HS may lead to serious complications, such as cutaneous squamous cell carcinoma (SCC) (also termed Marjolin ulcer). Herein, we report a case of invasive cutaneous SCC arising from chronic ulcers of a HS patient. A 40-year old Korean male, a current smoker with 20 pack-year history, presented with a history of painful, recurrent, deep-seated abscesses and ulcers on the buttocks since his late teens, thus classified as Hurley stage III. A large purulent ulcer developed on the right buttock several months ago. Initial treatment was focused on controlling infection and facilitating wound healing. The lesion showed 50% reduction of size in 6 weeks, but also developed foul odor and showed fungating margins. Multiple skin biopsies were consistent with invasive SCC. Magnetic resonance imaging revealed a few enlarged lymph nodes on the right inguinal area, which was confirmed as metastasis on frozen biopsy. Slow Mohs micrographic surgery and radical right inguinal lymph node dissection was done. Incidence rates of SCC arising from HS have been reported up to 4.6%. To our knowledge, this is the first report of cutaneous SCC arising from HS in Korea. Our case emphasizes that the diagnosis of cutaneous SCC in HS should not be delayed, and early surgical intervention is crucial for better outcomes.
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참고문헌 (7)
참고문헌 신청
Lavogiez C / 2010 / Clinicopathological study of 13 cases of squamous cell carcinoma complicating hidradenitis suppurativa / Dermatology 220:147~153
Huang C / 2017 / Successful surgical treatment for squamous cell carcinoma arising from hidradenitis suppurativa: a case report and literature review / Medicine (Baltimore) 96:e5857
Jourabchi N / 2017 / Squamous cell carcinoma complicating a chronic lesion of hidradenitis suppurativa: a case report and review of the literature / Int Wound J 14:435~438
Melnik BC / 2013 / Impaired Notch signalling : the unifying mechanism explaining the pathogenesis of hidradenitis suppurativa(acne inversa) / Br J Dermatol 168:876~878
Kantono M / 2017 / Inflammasomes and cancer : the dynamic role of the inflammasome in tumor development / Front Immunol 8:1132
Huang C / 2017 / Successful surgical treatment for squamous cell carcinoma arising from hidradenitis suppurativa: a case report and literature review / Medicine (Baltimore) 96:e5857
Jourabchi N / 2017 / Squamous cell carcinoma complicating a chronic lesion of hidradenitis suppurativa: a case report and review of the literature / Int Wound J 14:435~438
Melnik BC / 2013 / Impaired Notch signalling : the unifying mechanism explaining the pathogenesis of hidradenitis suppurativa(acne inversa) / Br J Dermatol 168:876~878
Kantono M / 2017 / Inflammasomes and cancer : the dynamic role of the inflammasome in tumor development / Front Immunol 8:1132
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