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자료유형
학술저널
저자정보
표정윤 (연세대학교) 송정식 (연세대학교) 박용범 (연세대학교) 이상원 (연세대학교)
저널정보
연세대학교 의과대학 Yonsei Medical Journal Yonsei Medical Journal 제61권 제11호
발행연도
2020.1
수록면
970 - 975 (6page)

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We investigated pregnancy morbidities in Korean patients with Takayasu arteritis (TA) in a single tertiary hospital as a pilot study. We retrospectively reviewed the medical records of 12 pregnancies in seven patients with TA. All patients were diagnosed with TAbased on the 1990 American College of Rheumatology classification criteria. The medical records of patients were well-documented,allowing review of clinical data including pregnancy morbidities. The angiographic and Ishikawa classifications at diagnosisand TA activity at delivery were assessed. Of the 12 pregnancies, two pregnancies ended in spontaneous abortion (16.7%), andone pregnancy (8.3%) had therapeutic abortion at 9 weeks due to maternal morbidity. Among the remaining nine pregnancies,only one child was delivered via normal spontaneous vaginal delivery, and the remaining eight were delivered by Caesarean section. Two out of nine (22.2%) neonates were born with low birth weight, and one of them was born at 30 weeks of gestation. Themost common maternal complication was hypertension affecting 7/12 (58.3%) pregnancies. Preeclampsia occurred in one pregnancy,and gestational diabetes mellitus (GDM) occurred in two pregnancies. At delivery, disease activity of TA was stable in allpregnancies, and glucocorticoids were administered in nine pregnancies. Live birth rate of pregnant Korean patients with TA was75%. Future studies are needed to reduce pregnancy-related complications.

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