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논문 기본 정보

자료유형
학술저널
저자정보
조진모 (가톨릭관동대학교) 성경수 (동아대학교) 정인호 (연세대학교) 장원석 (연세대학교) 정현호 (연세대학교) 장종희 (연세대학교)
저널정보
연세대학교 의과대학 Yonsei Medical Journal Yonsei Medical Journal 제61권 제11호
발행연도
2020.1
수록면
976 - 980 (5page)

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Cavernous hemangiomas occur very rarely in the cavernous sinus. This study aimed to evaluate the efficacy of Gamma Knife surgery(GKS) on cavernous sinus cavernous hemangioma (CSCH) and to analyze the temporal volume change. We retrospectivelyreviewed the clinical data of 26 CSCH patients who were treated with GKS between 2001 and 2017. Before GKS, 11 patients(42.3%) had cranial neuropathies and 5 patients (19.2%) complained of headache, whereas 10 patients (38.5%) were initially asymptomatic. The mean pre-GKS mass volume was 9.3 mL (range, 0.5?31.6 mL), and the margin dose ranged from 13 to 15 Gy accordingto the mass volume and the proximity to the optic pathway. All cranial neuropathy patients and half of headache patientsshowed clinical improvement. All 26 patients achieved mass control; remarkable responses (less than 1/3 of the initial mass volume)were shown in 19 patients (73.1%) and moderate responses (more than 1/3 and less than 2/3) in 7 patients (26.9%). Themean final mass volume after GKS was 1.8 mL (range, 0?12.6 mL). The mean mass volume at 6 months after GKS was 45% (range,5?80%) compared to the mass volume before GKS and 21% (range, 0?70%) at 12 months. The higher radiation dose tended to inducemore rapid and greater volume reduction. No treatment-related complication was observed during the follow-up period. GKS could be an effective and safe therapeutic strategy for CSCH. GKS induced very rapid volume reduction compared to otherbenign brain tumors.

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