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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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Background: As an instrument for measuring body composition in experimental animals, dual energy X-ray absorptiometry (DXA) is ideal for accuracy, cost, and measurement efficiency. However, there is too little insight into the effectiveness of the various aspects of applying DXA to experimental animals. We investigated whether to compare and verify the precision and accuracy of DXA and nuclear magnetic resonance (NMR) animal body composition analyzers. Methods: We used 30 Institution of Cancer Research mice in the study. First, in order to evaluate the reproducibility of DXA and NMR, we did repeated measurements by repositioning each mouse in anesthesia and euthanasia states. Subsequently, the accuracy of each device was evaluated by comparing the weight measured before the experiment, the weight of the tissue extracted from the mice after the experiment, and the measured DXA and NMR. In addition, when measuring the body composition of animals, we compared the time and the measurable body composition parameters and summarized the advantages and disadvantages of the 2 devices. Results: Compared to NMR, DXA had the advantage of a fast measurement of bone composition and rapid image analysis. In addition, DXA showed a higher correlation (>95%) with fat mass, lean mass baseline than did NMR (>85%). Conclusions: In conclusion, DXA was confirmed to have higher precision and measurement accuracy than did NMR. Therefore, DXA is an effective method for evaluating the body composition of experimental animals.
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참고문헌 (25)
참고문헌 신청
Junod SW / FDA and clinical drug trials: a short history
Mak IW / 2014 / Lost in translation : animal models and clinical trials in cancer treatment / Am J Transl Res 6:114~118
A. R. Behnke / 1995 / THE SPECIFIC GRAVITY OF HEALTHY MEN: BODY WEIGHT + VOLUME AS AN INDEX OF OBESITY / Obesity Research 3(3):295~300
Dempster P / 1995 / A new air displacement method for the determination of human body composition / Med Sci Sports Exerc 27:1692~1697
Siri WE / 1993 / Body composition from fluid spaces and density: analysis of methods. 1961 / Nutrition 9:480~491
Mak IW / 2014 / Lost in translation : animal models and clinical trials in cancer treatment / Am J Transl Res 6:114~118
A. R. Behnke / 1995 / THE SPECIFIC GRAVITY OF HEALTHY MEN: BODY WEIGHT + VOLUME AS AN INDEX OF OBESITY / Obesity Research 3(3):295~300
Dempster P / 1995 / A new air displacement method for the determination of human body composition / Med Sci Sports Exerc 27:1692~1697
Siri WE / 1993 / Body composition from fluid spaces and density: analysis of methods. 1961 / Nutrition 9:480~491
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