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논문 기본 정보
- 자료유형
- 학술대회자료
- 저자정보
- 발행연도
- 2021.10
- 수록면
- 299 - 299 (1page)
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초록· 키워드
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Transient receptor potential (TRP) channels play an essential role as environmental sensors in primary afferent neurons. The transient receptor potential vanilloid type 1 (TRPV1) channel, also known as the capsaicin receptor, is critical to chemical and physical sensation, and is regulated by anesthetic chemicals through an unknown mechanism. In the present study, we investigated the effect of gomisin A on human TRPV1 channel activity. Schisandra chinensis contains bio-active compounds such as the gomisin derivatives and their related compounds. Co-application with gomisin A inhibited the capsaicin-mediated inward peak current. This inhibitory effect of gomisin A on capsaicin-induced inward current showed concentration-dependence, and was ... 전체 초록 보기
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