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논문 기본 정보
- 자료유형
- 학술대회자료
- 저자정보
- 발행연도
- 2021.10
- 수록면
- 369 - 369 (1page)
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Natural products (NPs) are important for drug discovery and development; however their discovery is challenged by the wide inactivation or silence of microbial biosynthetic pathways. Currently strategies targeting this problem are mainly concentrated on chromosome dissembling, transcription, and translation-stage regulations as well as chemical stimulation. In this study, we applied to in vitro CRISPR/Cas9 to awake cryptic/silenced microbial biosynthetic genes, which show the low expression level, ovmF gene, through ... 전체 초록 보기
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