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논문 기본 정보
- 자료유형
- 학술대회자료
- 저자정보
- 발행연도
- 2021.10
- 수록면
- 385 - 385 (1page)
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이 논문의 연구 히스토리 (4)
2021
Dynamic Regulation to Improve Production of 3-hydroxypropionic Acid by Supplying Redox Cofactors
Yuchan KIM
,
Sung Kuk LEE
한국생물공학회 학술대회
2021.10
학술대회자료
Development of Dynamic Regulation Switch for Supply of Redox Cofactors Necessary for the Production of 3-Hydroxypropionic Acid
Yuchan KIM
,
Sung Kuk LEE
한국생물공학회 학술대회
2021.04
학술대회자료
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3-Hydroxypropionic acid (3-HP) is a platform chemical that can be used as the precursor for the production of valuable compounds, including acrylic acid and 1,3-propandiol. Using glucose as the substrate, Escherichia coli can synthesize 3-HP from malonyl-CoA, by heterologous expression of malonyl-CoA reductase, the enzyme derived from Chloroflexus aurantiacus. However, requirement of additional redox cofactors is limiting factor of this pathway. Excess amounts of redox cofactors are necessary for the production, though it causes growth defection once it is accumul^_@span style=color:#999999 ^_# ... ^_@/span^_#^_@a href=javascript:; onclick=onClickReadNode('NODE10675076');fn_statistics('Z354','null','null'); style='color:#999999;font-size:14px;text-decoration:underline;' ^_#전체 초록 보기^_@/a^_#
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3-Hydroxypropionic acid의 생산 경로와 이를 생산하는 미생물 균주
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Terminal (ω) - functionalized long chain carboxylic acids with redox balancing system in engineered Escherichia coli
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Transformer-based NAD/NADP Cofactor Analysis Pipeline Provides Insights on Classification and Engineering of Enzymes
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