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논문 기본 정보
- 자료유형
- 학술대회자료
- 저자정보
- 발행연도
- 2021.10
- 수록면
- 461 - 461 (1page)
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Several studies have conducted on neutralizing antibodies (NAbs) against influenza A viruses causing loss of life and economic damage. However, these virustatic antibodies lacking virucidal activity showed limited antiviral potency. Here, we develop a nanodisc providing the immunoglobulins with virucidal efficacy by rupturing the viral envelope, resulting in enhancing the antiviral effects. Mechanistically, the nanodiscs carrying Fc-binding peptides bind to NAbs targeting stem region of hemagglutinin are co-endocytosed into host cell ... 전체 초록 보기
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