지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.1
- 수록면
- 122 - 128 (7page)
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초록· 키워드
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Objectives: This study aims to develop and validate a country specific osteoporosis risk assessing tool for Sri Lankan postmenopausal women. Methods: Community-dwelling postmenopausal women were enrolled to development (n ¼ 602) and validation (n ¼ 339) samples. Clinical risk factors (CRFs) of osteoporosis were assessed. Bone mineral densities (BMD) of femoral neck, total hip and lumbar spine were assessed by dual energy X-ray absorptiometry (DXA) scan. Radial ultrasound (US) bone scan was done. Linear regression analysis was performed in development sample considering regional BMDs as dependent and CRFs as independent variables. Regression equations were developed to estimate regional BMDs using best predictive CRFs. Sensitivity, specificity, positive and negative predictive values (PPV and NPV) were assessed to validate the new tools. Results: Age, body weight and US T-scores showed positive correlations with BMDs of all 3 sites. Two osteoporosis risk assessing tools (OPRATs) were developed as OPRAT-1 and OPRAT-2. Prevalence of osteoporosis, in the validation sample was 74.3%. Sensitivity were high in both tools (OPRAT-1 and OPRAT-2; 83.2% and 82.5%) while specificity were moderate (44.8% for both). PPV of OPRAT-1 and OPRAT2 were 79.5% and 81.2%. Both tools showed moderate NPV (OPRAT-1 and OPRAT-2; 51% and 47%). Conclusions: Both OPRAT-1 and OPRAT-2 have high performance in screening postmenopausal women in Sri Lanka for risk of osteoporosis. OPRAT-2 is more convenient and can be used in any healthcare setting with limited resources to identify women who will be benefitted by DXA. OPRAT-1 can be used if the radial US facility is available.
목차
등록된 정보가 없습니다.
참고문헌 (32)
참고문헌 신청
Alquaiz AM / 2014 / Prevalence and factors associated with low bone mineral density in Saudi women : a community based survey / BMC Muscoskel Disord 15:5
International osteoporosis foundation / Epidemiology
Lekamwasam S / 2007 / Prevalence of osteoporosis among postmenopausal women in Sri Lanka : a cross-sectional community study / APLAR J Rheumatol 10:234~238
Tuzun S / 2012 / Incidence of hip fracture and prevalence of osteoporosis in Turkey : the FRACTURK study / Osteoporos Int 23:949~955
Ahlborg HG / 2010 / Prevalence of osteoporosis and incidence of hip fracture in women - secular trends over 30 years / BMC Muscoskel Disord 11:48
International osteoporosis foundation / Epidemiology
Lekamwasam S / 2007 / Prevalence of osteoporosis among postmenopausal women in Sri Lanka : a cross-sectional community study / APLAR J Rheumatol 10:234~238
Tuzun S / 2012 / Incidence of hip fracture and prevalence of osteoporosis in Turkey : the FRACTURK study / Osteoporos Int 23:949~955
Ahlborg HG / 2010 / Prevalence of osteoporosis and incidence of hip fracture in women - secular trends over 30 years / BMC Muscoskel Disord 11:48
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