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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.1
- 수록면
- 1 - 9 (9page)
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초록· 키워드
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Background: This study aimed to investigate the survival and morbidities of infants in the Korean Neonatal Network (KNN) with birth weight (BW) < 500 g. Methods: The demographic and clinical data of 208 live-born infants with a BW < 500 g at a gestational age of ≥ 22 weeks who were treated in the neonatal intensive care units of the KNN between 2013 and 2017 were reviewed. Results: The survival rate of the infants was 28%, with a median gestational age and BW of 243/7 weeks (range, 220/7–336/7) and 440 g (range, 220–499), respectively. Multivariable Cox proportional hazards analysis demonstrated that survival to discharge was associated with longer gestation, higher BW, female sex, singleton gestation, use of any antenatal corticosteroids, and higher Apgar scores at 5 minutes. The overall survival rates were significantly different between the BW categories of < 400 g and 400–499 g. However, there was no significant difference in the incidence of any morbidity between the BW groups. Half of the deaths of infants with BW < 500 g occurred within a week of life, mainly due to cardiopulmonary and neurologic causes. The major causes of death in infants after 1 week of age were infection and gastrointestinal disease. Among the surviving infants, 79% had moderate to severe bronchopulmonary dysplasia, 21% underwent surgical ligation of patent ductus arteriosus, 12% had severe intraventricular hemorrhage (grade III–IV), 38% had sepsis, 9% had necrotizing enterocolitis (stage ≥ 2), and 47% underwent laser treatment for retinopathy of prematurity. The median length of hospital stay was 132 days (range, 69–291), and 53% required assistive devices at discharge. Conclusion: Despite recent advances in neonatal intensive care, the survival and morbidity rates of infants with BW < 500 g need further improvement.
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참고문헌 (26)
참고문헌 신청
Draper ES / 1999 / Prediction of survival for preterm births by weight and gestational age : retrospective population based study / BMJ 319(7217):1093~1097
Tyson JE / 2008 / Intensive care for extreme prematurity--moving beyond gestational age / N Engl J Med 358(16):1672~1681
Patel RM / 2017 / Survival of infants born at periviable gestational ages / Clin Perinatol 44(2):287~303
Shim JW / 2015 / Changes in survival rate for very-low-birth-weight infants in Korea : comparison with other countries / J Korean Med Sci 30(Suppl 1):S25~S34
American College of Obstetricians and Gynecologists / 2009 / ACOG Practice Bulletin No. 101: Ultrasonography in pregnancy / Obstet Gynecol 113(2 Pt 1):451~461
Tyson JE / 2008 / Intensive care for extreme prematurity--moving beyond gestational age / N Engl J Med 358(16):1672~1681
Patel RM / 2017 / Survival of infants born at periviable gestational ages / Clin Perinatol 44(2):287~303
Shim JW / 2015 / Changes in survival rate for very-low-birth-weight infants in Korea : comparison with other countries / J Korean Med Sci 30(Suppl 1):S25~S34
American College of Obstetricians and Gynecologists / 2009 / ACOG Practice Bulletin No. 101: Ultrasonography in pregnancy / Obstet Gynecol 113(2 Pt 1):451~461
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