지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.1
- 수록면
- 933 - 942 (10page)
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초록· 키워드
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Background: Evidence regarding the association between variabilities in obesity measures and health outcomes is limited. We aimed to examine the association between variabilities in obesity measures and cardiovascular outcomes and all-cause mortality. Methods: We identified 4,244,460 individuals who underwent health examination conducted by the Korean National Health Insurance Service during 2012, with ≥3 anthropometric measurements between 2009 and 2012. Variabilities in body weight (BW) and waist circumference (WC) were assessed using four indices including variability independent of the mean (VIM). We performed multivariable Cox proportional hazards regression analyses. Results: During follow-up of 4.4 years, 16,095, 18,957, and 30,200 cases of myocardial infarction (MI), stroke, and all-cause mortality were recorded. Compared to individuals with the lowest quartiles, incrementally higher risks of study outcomes and those of stroke and all-cause mortality were observed among individuals in higher quartiles of VIM for BW and VIM for WC, respectively. The multivariable adjusted hazard ratios and 95% confidence intervals comparing the highest versus lowest quartile groups of VIM for BW were 1.17 (1.12 to 1.22) for MI, 1.20 (1.16 to 1.25) for stroke, and 1.66 (1.60 to 1.71) for all-cause mortality; 1.07 (1.03 to 1.12) for stroke and 1.29 (1.25 to 1.33) for all-cause mortality regarding VIM for WC. These associations were similar with respect to the other indices for variability. Conclusion: This study revealed positive associations between variabilities in BW and WC and cardiovascular outcomes and all cause mortality. Our findings suggest that variabilities in obesity measures are associated with adverse health outcomes in the general population.
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참고문헌 (30)
참고문헌 신청
Flegal KM / 2013 / Association of all-cause mortality with overweight and obesity using standard body mass index categories : a systematic review and meta-analysis / JAMA 309:71~82
Rosengren A / 1999 / Body weight and weight gain during adult life in men in relation to coronary heart disease and mortality : a prospective population study / Eur Heart J 20:269~277
Berentzen T / 2006 / Effects of intended weight loss on morbidity and mortality : possible explanations of controversial results / Nutr Rev 64:502~507
Harrington M / 2009 / A review and metaanalysis of the effect of weight loss on all-cause mortality risk / Nutr Res Rev 22:93~108
Strohacker K / 2009 / Consequences of weight cycling: an increase in disease risk? / Int J Exerc Sci 2:191~201
Rosengren A / 1999 / Body weight and weight gain during adult life in men in relation to coronary heart disease and mortality : a prospective population study / Eur Heart J 20:269~277
Berentzen T / 2006 / Effects of intended weight loss on morbidity and mortality : possible explanations of controversial results / Nutr Rev 64:502~507
Harrington M / 2009 / A review and metaanalysis of the effect of weight loss on all-cause mortality risk / Nutr Res Rev 22:93~108
Strohacker K / 2009 / Consequences of weight cycling: an increase in disease risk? / Int J Exerc Sci 2:191~201
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