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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 143 - 148 (6page)
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초록· 키워드
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Purpose: This study aimed to develop a multi-channel near-infrared spectroscopy (NIRS) and ultrasonography (USG) fusion imaging system for imaging prostate cancer and to verify its diagnostic capability by applying the hybrid imaging system to a prostate cancer phantom. Methods: A multi-channel NIRS system using the near-infrared 785-nm wavelength with 12 channels and four detectors was developed. After arranging the optical fibers around a USG transducer, we performed NIRS imaging and grayscale USG imaging simultaneously. Fusion imaging was obtained by processing incoming signals and the spatial reconstruction of NIRS, which corresponded with grayscale USG acquired at the same time. The NIRS-USG hybrid system was applied to a silicone-based optical phantom of the prostate gland containing prostate cancer to verify its diagnostic capability qualitatively. Results: The NIRS-USG hybrid imaging system for prostate cancer imaging simultaneously provided anatomical and optical information with 2-dimensional registration. The hybrid imaging system showed more NIR attenuation over the prostate cancer model than over the model of normal prostate tissue. Its diagnostic capability to discriminate a focal area mimicking the optical properties of prostate cancer from the surrounding background mimicking the optical properties of normal prostate tissue was verified by applying the hybrid system to a silicone-based optical phantom of prostate cancer. Conclusion: This study successfully demonstrated that the NIRS-USG hybrid system may serve as a new imaging method for improving the diagnostic accuracy of prostate cancer, with potential utility for future clinical applications.
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참고문헌 (19)
참고문헌 신청
Torre LA / 2015 / Global cancer statistics, 2012 / CA Cancer J Clin 65:87~108
Siegel RL / 2016 / Cancer statistics, 2016 / CA Cancer J Clin 66:7~30
Hodge KK / 1989 / Random systematic versus directed ultrasound guided transrectal core biopsies of the prostate / J Urol 142:71~74
Djavan B / 2001 / Prospective evaluation of prostate cancer detected on biopsies 1, 2, 3 and 4: when should we stop? / J Urol 166:1679~1683
Guichard G / 2007 / Extended 21-sample needle biopsy protocol for diagnosis of prostate cancer in 1000 consecutive patients / Eur Urol 52:430~435
Siegel RL / 2016 / Cancer statistics, 2016 / CA Cancer J Clin 66:7~30
Hodge KK / 1989 / Random systematic versus directed ultrasound guided transrectal core biopsies of the prostate / J Urol 142:71~74
Djavan B / 2001 / Prospective evaluation of prostate cancer detected on biopsies 1, 2, 3 and 4: when should we stop? / J Urol 166:1679~1683
Guichard G / 2007 / Extended 21-sample needle biopsy protocol for diagnosis of prostate cancer in 1000 consecutive patients / Eur Urol 52:430~435
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