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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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Background: Hematopoietic stem cell (HSC) transplantation is an important therapeutic option for many malignant and non-malignant diseases. The whole transplant process involves multiple areas and complex steps. The laboratory procedures include the collection, processing, and storage of HSC. The HSC registry aims to identify the current situation and draw improvement points by voluntarily registering the information of an HSC graft collected by each institute sharing the analyzed data. This study analyzed and shared the data for 2018. Methods: Data for 2018 registered at the HSC registry website (www.ksfa-registry.org) was downloaded and analyzed. The data were to enter the information of each collection and include the demography of the donors, transplant type, instrument, vascular access, mobilization modality, and the number of CD34＋ cells. Results: Two thousand eight hundred eighty-eight collection datasets from 1,373 donors were registered from 19 institutes, which was slightly higher than that reported in 2017. The number of collections in one patient was in the range of 1∼17 times, and the average was two times. In allogeneic HSCT, the number of related donors was higher than that of unrelated donors. The frequency of collecting more than four times per donor was 25.2% for autologous donors, compared to 95.4% for allogeneic donors less than twice. Conclusion: The HSC registry is not limited to identifying the current situation and sharing the analyzed data, but is expected to contribute to the development of guidelines, education of human resources, and the standardization of laboratory procedures involved in hematopoietic stem cell transplantation. (Korean J Blood Transfus 2020; 31:109-118)
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참고문헌 (13)
참고문헌 신청
The Korean Society of Blood and Marrow Transplantation / Annual statistics of HSCT 2018
Akkök CA / 2011 / Is there a scientific basis for a recommended standardization of collection and cryopreservation of peripheral blood stem cell grafts / Cytotherapy 13:1013~1024
Chabannon C / 2012 / Ten years after the first inspection of a candidate European centre, an EBMT registry analysis suggests that clinical outcome is improved when hematopoietic SCT is performed in a JACIE accredited program / Bone Marrow Transplant 47:15~17
Snowden JA / 2020 / Benchmarking of survival outcomes following haematopoietic stem cell transplantation : a review of existing processes and the introduction of an international system from the European Society for Blood and Marrow Transplantation(EBMT)and the Joint Accreditation Committee of ISCT and EBMT(JACIE) / Bone Marrow Transplant 55:681~694
Song EY / 2008 / Establishment of a national on-line registry for apheresis in Korea / Transfus Apher Sci 38:93~100
Akkök CA / 2011 / Is there a scientific basis for a recommended standardization of collection and cryopreservation of peripheral blood stem cell grafts / Cytotherapy 13:1013~1024
Chabannon C / 2012 / Ten years after the first inspection of a candidate European centre, an EBMT registry analysis suggests that clinical outcome is improved when hematopoietic SCT is performed in a JACIE accredited program / Bone Marrow Transplant 47:15~17
Snowden JA / 2020 / Benchmarking of survival outcomes following haematopoietic stem cell transplantation : a review of existing processes and the introduction of an international system from the European Society for Blood and Marrow Transplantation(EBMT)and the Joint Accreditation Committee of ISCT and EBMT(JACIE) / Bone Marrow Transplant 55:681~694
Song EY / 2008 / Establishment of a national on-line registry for apheresis in Korea / Transfus Apher Sci 38:93~100
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