Successful Treatment of Severe Hemolytic Disease of the Newborn Caused by Anti-Jkb

Goo Lyeon Kim; Yoonsoo Kim; Young Pyo Chang; Ju-Hee Seo; Mee Jeong Lee

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자료유형: 학술저널

저자정보: Goo Lyeon Kim (Department of Pediatrics Dankook University Hospital Cheonan Korea) Yoonsoo Kim (Department of Pediatrics Dankook University Hospital Cheonan Korea) Young Pyo Chang (Department of Pediatrics Dankook University Hospital Cheonan Korea) Ju-Hee Seo (Department of Pediatrics Dankook University Hospital Cheonan Korea) Mee Jeong Lee (Department of Pediatrics Dankook University Hospital Cheonan Korea)

저널정보: 대한소아혈액종양학회 Clinical Pediatric Hematology-Oncology Clinical Pediatric Hematology-Oncology Vol.28 No.1

발행연도: 2021.1

수록면: 49 - 53 (5page)

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Hemolytic disease of the newborn (HDN) is a condition in which maternal antibodies cross the placenta and cause hemolytic reactions. Anti-RhD was the most common cause, but with the introduction of immunoglobulin, the frequency has decreased sig nificantly, making hemolytic d isease c aused by o ther minor b lood g roups more important. Kidd antigen is also known to cause hemolytic transfusion reactions. Only 13 cases have b een reported so far, b ecause K idd antig en dose not u sually c ause HDN. Most cases have a good outcome, and only two fatal cases have been reported. A four-day-old male patient was hospitalized for jaundice, and hemolysis was confirmed by blood test. The mother’s blood was Jkb antibody positive. The patient did not improve with phototherapy, so an exchange transfusion was performed. Additional hemolysis occurred, so we undertook transfusion of red blood cells, resulting in cessation of hemolysis. We report HDN caused by Jkb antibody that responded to exchange blood transfusion.

#Hemolytic disease of the newborn #Jaundice #Exchange transfusion #Kidd blood group #Anti-Jkb

참고문헌 (19)

참고문헌 신청

Moise KJ Jr / 1994 / Changing trends in the management of red blood cell alloimmunization in pregnancy / Arch Pathol Lab Med 118:421~428

Rath ME / 2011 / Hemato-logical morbidity and management in neonates with hemo-lytic disease due to red cell alloimmunization / Early Hum Dev 87:583~588

Allen FH / 1951 / A new blood-group antigen / Nature 167:482

Plaut G / 1953 / A new blood-group antibody, anti-Jkb / Nature 171:431

Lawicki S / 2017 / The Kidd(JK)blood group system / Transfus Med Rev 31:165~172

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