지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.1
- 수록면
- 89 - 100 (12page)
이용수
초록· 키워드
오류제보하기
Objectives: White-coat hypertension is defined as high blood pressure (BP) on clinical assessment but normal BP elsewhere or on ambulatory measurement. Autonomic dysfunction may be one of the mechanisms causing white-coat hypertension. Slowed heart rate recovery and excessive BP response during exercise test are associated with autonomic dysfunction. The purpose of this study was to determine the association between white-coat hypertension and abnormal autonomic nervous system response. Methods: We assessed 295 patients stratified into three groups via 24hr ambulatory BP monitoring, following 2017 ACC/AHA guidelines : normal BP group, white-coat hypertension group, and a hypertension group. We analyzed medical history, blood test, echocardiography, 24hr ambulatory BP monitoring, and exercise test data. Results: There was no difference in basement characteristics and echocardiography among the groups. Blunted heart rate recovery of each group showed a significant difference. Control group had 0% blunted heart rate recovery, but 33.3% in white coat group and 27.6% in true hypertension group (P < 0.001). Also, in the control group, 4.5% showed excessive BP response, but 31.5% in the white coat hypertension group and 29.3% in the true hypertension group (P < 0.001). Excessive BP response during the exercise test or blunted heart rate recovery, which is an indicator of autonomic nervous system abnormality, was more common in the hypertensive group and white-coat hypertension group than in the normal BP group. Conclusions: These results confirmed that white-coat hypertension has an autonomic nervous system risk. Therefore, white-coat hypertension can be a future cardiovascular risk factor.
목차
등록된 정보가 없습니다.
참고문헌 (30)
참고문헌 신청
Kwang-Il Kim / 2019 / 2018 Korean society of hypertension guidelines for the management of hypertension: part III-hypertension in special situations / Clinical Hypertension 25(4):75~88
Mariampillai JE / 2017 / Exercise systolic blood pressure at moderate workload predicts cardiovascular disease and mortality through 35 years of follow-up in healthy, middle-aged men / Blood pressure 26:229~236
Mancia G / 2014 / The autonomic nervous system and hypertension / Circ Res 114:1804~1814
Miyai N / 2005 / Ambulatory blood pressure, sympathetic activity, and left ventricular structure and function in middle-aged normotensive men with exaggerated blood pressure response to exercise / Med Sci Monit 11:Cr478~Cr484
Singh JP / 1999 / Blood pressure response during treadmill testing as a risk factor for new-onset hypertension. The Framingham heart study / Circulation 99:1831~1836
Mariampillai JE / 2017 / Exercise systolic blood pressure at moderate workload predicts cardiovascular disease and mortality through 35 years of follow-up in healthy, middle-aged men / Blood pressure 26:229~236
Mancia G / 2014 / The autonomic nervous system and hypertension / Circ Res 114:1804~1814
Miyai N / 2005 / Ambulatory blood pressure, sympathetic activity, and left ventricular structure and function in middle-aged normotensive men with exaggerated blood pressure response to exercise / Med Sci Monit 11:Cr478~Cr484
Singh JP / 1999 / Blood pressure response during treadmill testing as a risk factor for new-onset hypertension. The Framingham heart study / Circulation 99:1831~1836
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