지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.1
- 수록면
- 65 - 68 (4page)
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초록· 키워드
오류제보하기
Background: New-onset refractory status epilepticus (NORSE) refers to the newly established concept of a disease characterized by refractory status epilepticus without an identifiable etiology. Recent reports have indicated the importance of immunotherapy for NORSE. Case Report: A 37-year-old man with no past history of epilepsy was admitted for a presenting complaint of confusion. He was treated with acyclovir and anti-epileptic drug (AED) for presumed herpes encephalitis. However, he developed generalized tonic-clonic seizures on day 6 of admission that worsened despite treatment with multiple AEDs. NORSE was considered to be a probable diagnosis and immunotherapy with methylprednisolone and immunoglobulin was scheduled. However, persistent seizure activity was observed on the electroencephalogram after the completion of initial immunotherapy. Subsequently, rituximab was administered for 4 weeks. He eventually regained consciousness and was able to resume social activity. Conclusion: Our patient exhibited a favorable outcome with early-intensive immunotherapy and subsequent rituximab treatment for NORSE.
목차
등록된 정보가 없습니다.
참고문헌 (10)
참고문헌 신청
Mayer SA / 2002 / Refractory status epilepticus : frequency, risk factors, and impact on outcome / Arch Neurol 59:205~210
Hocker SE / 2013 / Predictors of outcome in refractory status epilepticus / JAMA Neurol 70:72~77
Gaspard N / 2018 / New-onset refractory status epilepticus(NORSE)and febrile infection-related epilepsy syndrome(FIRES) : state of the art and perspectives / Epilepsia 59:745~752
Shin JW / 2018 / Clinical characterization of unknown/cryptogenic status epilepticus suspected as encephalitis : a multicenter cohort study / J Neuroimmunol 315:1~8
Hermetter C / 2018 / Systematic review : syndromes, early diagnosis, and treatment in autoimmune encephalitis / Front Neurol 9:706
Hocker SE / 2013 / Predictors of outcome in refractory status epilepticus / JAMA Neurol 70:72~77
Gaspard N / 2018 / New-onset refractory status epilepticus(NORSE)and febrile infection-related epilepsy syndrome(FIRES) : state of the art and perspectives / Epilepsia 59:745~752
Shin JW / 2018 / Clinical characterization of unknown/cryptogenic status epilepticus suspected as encephalitis : a multicenter cohort study / J Neuroimmunol 315:1~8
Hermetter C / 2018 / Systematic review : syndromes, early diagnosis, and treatment in autoimmune encephalitis / Front Neurol 9:706
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