지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 248 - 254 (7page)
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초록· 키워드
오류제보하기
Objective. This study examined the prevalence of low-bone mineral density (BMD) and its associated factors in Korean children and adolescents with juvenile idiopathic arthritis (JIA). Methods. Thirty-nine patients with JIA were included in this cross-sectional study. The patients were examined for their bone age (BA) and bone mineral density (BMD). The BMD was measured using dual-energy X-ray absorptiometry on the lumbar spine. Each BMD value was converted to a Z-score by comparing the reference values of the healthy control group in terms of the age and sex of each patient, which was measured using the same device. A Z-score of less than −2.0 was defined as a low BMD. Laboratory tests were performed to detect the serum calcium, phosphorus, alkaline phosphatase, and 25-hydroxyvitamin D levels. Results. The mean age at the time of the examination was 12.2±3.6 years, and the study comprised a total of 39 patients (16 males, 23 females). Patients with systemic JIA had a lower BMD, which was calculated based on the CA, BA, and HA, than those with non-systemic JIA (P=0.020, P=0.049, and P=0.024, respectively); the corticosteroid user group also showed a lower BMD, which had been calculated based on the CA, BA, and HA, than the corticosteroid non-user group (p=0.002, p=0.022, and p=0.188, respectively). Conclusion. This study suggests that JIA patients have a lower BMD than control subjects. Therefore, treatment, and education are warranted while treating patients with JIA, particularly those requiring oral corticosteroids or those with systemic JIA and appropriate laboratory tests.
목차
등록된 정보가 없습니다.
참고문헌 (31)
참고문헌 신청
Petty RE / 2015 / Textbook of pediatric rheumatology e-book / Elsevier Health Sciences
Naka H / 2005 / Effects of pubertal development, height, weight, and grip strength on the bone mineral density of the lumbar spine and hip in peripubertal Japanese children: Kyoto kids increase density in the skeleton study (Kyoto KIDS study) / J Bone Miner Metab 23:463~469
Brabnikova Maresova K / 2011 / Secondary osteoporosis in patients with juvenile idiopathic arthritis / J Osteoporos 2011:569417
McDonagh JE / 2001 / Osteoporosis in juvenile idiopathic arthritis / Curr Opin Rheumatol 13:399~404
Masi L / 2002 / Association of low bone mass with vitamin d receptor gene and calcitonin receptor gene polymorphisms in juvenile idiopathic arthritis / J Rheumatol 29:2225~2231
Naka H / 2005 / Effects of pubertal development, height, weight, and grip strength on the bone mineral density of the lumbar spine and hip in peripubertal Japanese children: Kyoto kids increase density in the skeleton study (Kyoto KIDS study) / J Bone Miner Metab 23:463~469
Brabnikova Maresova K / 2011 / Secondary osteoporosis in patients with juvenile idiopathic arthritis / J Osteoporos 2011:569417
McDonagh JE / 2001 / Osteoporosis in juvenile idiopathic arthritis / Curr Opin Rheumatol 13:399~404
Masi L / 2002 / Association of low bone mass with vitamin d receptor gene and calcitonin receptor gene polymorphisms in juvenile idiopathic arthritis / J Rheumatol 29:2225~2231
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