지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 296 - 302 (7page)
이용수
초록· 키워드
오류제보하기
Dental maturity is associated with skeletal maturity, which is advanced in girls with central precocious puberty (CPP). We investigated the performance of dental maturity as a screening method for CPP using mandibular second premolar and molar calcification stages, assessed the associated anthropometric and laboratory factors, and evaluated pubertal response predictors using the gonadotropin-releasing hormone stimulation test (GnRHST) in prepubertal and pubertal girls. A prospective case-control study was conducted in girls, aged 7.0–8.9 years, classified into pubertal (peak luteinizing hormone [LH] after GnRHST ≥ 5 IU/L), prepubertal (peak LH < 5 IU/L), and control groups. Auxological and biochemical tests, panoramic radiographs, and GnRHSTs in participants with breast development were conducted. Dental maturity was assessed using the Demirjian index (DI). We included 103 girls (pubertal, 40; prepubertal, 19; control, 44). Chronological age (CA) was not significantly different between groups. Bone age (BA) and BA advancement was higher in the pubertal and prepubertal groups. Increased DI values at the mandibular second premolar and molar were significantly associated with CA, BA, BA advancement, height standard deviation score (SDS), peak LH after GnRHST, and insulin-like growth factor-I (IGF-I) (all P < 0.05). Moreover, odds ratio (OR) of the mandibular second premolar and molar (a DI value of ≥ E) for predicting a positive response to GnRHST was 8.7 (95% confidence intervals [CI], 2.9–26.1) and 5.2 (95% CI, 2.2–12.7), respectively. Dental maturity was a strong predictor for diagnosing CPP. Determining dental maturity in girls with suspected precocious puberty might help determine the performance of GnRHSTs.
목차
등록된 정보가 없습니다.
참고문헌 (34)
참고문헌 신청
Lee PA / 1999 / Central precocious puberty. An overview of diagnosis, treatment, and outcome / Endocrinol Metab Clin North Am 28:901~918
Carel JC / 2008 / Clinical practice. Precocious puberty / N Engl J Med 358:2366~2377
Brauner R / 1994 / Adult height in girls with idiopathic true precocious puberty / J Clin Endocrinol Metab 79:415~420
Mrug S / 2008 / Positive parenting and early puberty in girls : protective effects against aggressive behavior / Arch Pediatr Adolesc Med 162:781~786
Lee PA / 1994 / Laboratory monitoring of children with precocious puberty / Arch Pediatr Adolesc Med 148:369~376
Carel JC / 2008 / Clinical practice. Precocious puberty / N Engl J Med 358:2366~2377
Brauner R / 1994 / Adult height in girls with idiopathic true precocious puberty / J Clin Endocrinol Metab 79:415~420
Mrug S / 2008 / Positive parenting and early puberty in girls : protective effects against aggressive behavior / Arch Pediatr Adolesc Med 162:781~786
Lee PA / 1994 / Laboratory monitoring of children with precocious puberty / Arch Pediatr Adolesc Med 148:369~376
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