Effect of Social Deprivation on the Stage and Mode of Presentation of Colorectal Cancer

Ahmed ELHadi; Sarah Ashford-Wilson; Stephanie Brown; Atanu Pal; Roshan Lal; Kamal Aryal

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자료유형: 학술저널

저자정보: Ahmed ELHadi (James Paget University Hospital) Sarah Ashford-Wilson (James Paget University Hospital) Stephanie Brown (James Paget University Hospital) Atanu Pal (James Paget University Hospital) Roshan Lal (James Paget University Hospital) Kamal Aryal (James Paget University Hospital)

저널정보: 대한대장항문학회 Annals of Coloproctology Annals of Coloproctolgy Vol.32 No.4

발행연도: 2016.1

수록면: 128 - 132 (5page)

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Purpose: Based in a hospital serving one of the most deprived areas in the United Kingdom (UK), we aimed to investigate, using the Indices of Deprivation 2010, the hypothesis that deprivation affects the stage and mode of presentation of colorectal cancer. Methods: All newly diagnosed patients with colorectal cancer presenting to a District General Hospital in the UK between January 2010 and December 2014 were included. Data were collected from the Somerset National Cancer Database. The effect of social deprivation, measured using the Index of Multiple Deprivation Score, on the stage and mode of presentation was evaluated utilizing Microsoft Excel and IBM SPSS ver. 22.0. Results: A total of 701 patients (54.5% male; mean age, 76 years) were included; 534 (76.2%) underwent a surgical procedure, and 497 (70.9%) underwent a colorectal resection. Of the patients undergoing a colorectal resection, 86 (17.3%) had an emergency surgical resection. Social deprivation was associated with Duke staging (P = 0.09). The 90-day mortality in patients undergoing emergency surgery was 12.8% compared to 6.8% in patients undergoing elective surgery (P = 0.06). No association was found between deprivation and emergency presentation (P = 0.97). A logistic regression analysis showed no increase in the probability of metastasis amongst deprived patients. Conclusion: This study suggests an association between deprivation and the stage of presentation of colorectal cancer. Patients undergoing emergency surgery tend to have a higher 90-day mortality rate, although this was not related to deprivation. This study highlights the need to develop an individual measure to assess social deprivation.

참고문헌 (22)

참고문헌 신청

Holleczek B / 2015 / On-going improvement and persistent differences in the survival for patients with colon and rectum cancer across Europe 1999-2007 - Results from the EUROCARE-5 study / Eur J Cancer 51:2158~2168

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SEER Cancer Statistics Review, 1975-2012

Health and Social Care Information Centre / 2014 / National Bowel Cancer Audit Report 2014

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