지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 286 - 291 (6page)
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초록· 키워드
오류제보하기
Background: We investigated the hypothesis that pretreatment with nefopam 20 mg would influence the onset and recovery profiles of rocuronium-induced neuromuscular block. Methods: After Institutional Review Board approval, 134 patients, aged between 20–65 years, belonging to the American Society of Anesthesiologists physical status classification I or II, were randomly allocated to receive either 0.9% normal saline (control group) or nefopam 20 mg (nefopam group), infused over one hour before induction of anesthesia. Anesthesia was induced with remifentanil and propofol, followed by endotracheal intubation with rocuronium 0.6 mg/kg. We recorded the lag time, onset time, clinical duration, recovery index, recovery time, and total recovery time. Results: We included 111 patients in the final analysis. The lag time, onset time, clinical duration, recovery index, recovery time, and total recovery time of the nefopam group (n = 57) were not significantly different compared with that of the control group (n = 54). Conclusions: Pretreatment with nefopam 20 mg one hour before induction of anesthesia does not have a significant influence on the onset and recovery profiles of rocuronium- induced neuromuscular block.
목차
등록된 정보가 없습니다.
참고문헌 (27)
참고문헌 신청
김경훈 / 2014 / Rediscovery of Nefopam for the Treatment of Neuropathic Pain / The Korean Journal of Pain 27(2):103~111
Gregori-Puigjane E / 2012 / Identifying mechanism-of-action targets for drugs and probes / Proc Natl Acad Sci U S A 109:11178~11183
Chanques G / 2011 / Analgesic efficacy and haemodynamic effects of nefopam in critically ill patients / Br J Anaesth 106:336~343
Spacek A / 1999 / Rocuronium-induced neuromuscular block is affected by chronic carbamazepine therapy / Anesthesiology 90:109~112
Koenig HM / 1999 / The effect of anticonvulsant therapy on two doses of rocuronium-induced neuromuscular blockade / J Neurosurg Anesthesiol 11:86~89
Gregori-Puigjane E / 2012 / Identifying mechanism-of-action targets for drugs and probes / Proc Natl Acad Sci U S A 109:11178~11183
Chanques G / 2011 / Analgesic efficacy and haemodynamic effects of nefopam in critically ill patients / Br J Anaesth 106:336~343
Spacek A / 1999 / Rocuronium-induced neuromuscular block is affected by chronic carbamazepine therapy / Anesthesiology 90:109~112
Koenig HM / 1999 / The effect of anticonvulsant therapy on two doses of rocuronium-induced neuromuscular blockade / J Neurosurg Anesthesiol 11:86~89
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