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논문 기본 정보

자료유형
학술저널
저자정보
김형수 (연세대학교) 김태훈 (연세대학교) 차명진 (서울대학교) 이정명 (경희대학교) 박준범 (이화여자대학교) 박진규 (한양대학교) 강기운 (을지대학교) 심재민 (고려대학교) 엄재선 (연세대학교) 김준 (울산대학교) 박형욱 (전남대학교) 최의근 (서울대학교) 김진배 (경희대학교) 김창수 (연세대학교) 이영수 (대구가톨릭대학교) 정보영 (연세대학교)
저널정보
대한심장학회 Korean Circulation Journal Korean Circulation Journal Vol.47 No.6
발행연도
2017.1
수록면
877 - 887 (11page)

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Background and Objectives: The aging population is rapidly increasing, and atrial fibrillation (AF) is becoming a significant public health burden in Asia, including Korea. This study evaluated current treatment patterns and guideline adherence of AF treatment. Methods: In a prospective observational registry (COmparison study of Drugs for symptom control and complication prEvention of Atrial Fibrillation [CODE-AF] registry), 6,275 patients with nonvalvular AF were consecutively enrolled between June 2016 and April 2017 from 10 tertiary hospitals in Korea. Results: The AF type was paroxysmal, persistent, and permanent in 65.3%, 30.0%, and 2.9% of patients, respectively. Underlying structural heart disease was present in 11.9%. Mean CHA2DS2-VASc was 2.7±1.7. Oral anticoagulation (OAC), rate control, and rhythm control were used in 70.1%, 53.9%, and 54.4% of patients, respectively. OAC was performed in 82.7% of patients with a high stroke risk. However, antithrombotic therapy was inadequately used in 53.4% of patients with a low stroke risk. For rate control in 192 patients with low ejection fraction (<40%), β-blocker (65.6%), digoxin (5.2%), or both (19.3%) were adequately used in 90.1% of patients; however, a calcium channel blocker was inadequately used in 9.9%. A rhythm control strategy was chosen in 54.4% of patients. The prescribing rate of class Ic antiarrythmics, dronedarone, and sotalol was 16.9% of patients with low ejection fraction. Conclusion: This study shows how successfully guidelines can be applied in the real world. The nonadherence rate was 17.2%, 9.9%, and 22.4% for stroke prevention, rate control, and rhythm control, respectively.

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