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자료유형
학술저널
저자정보
Eun Young Joo (Inha University) Keun Young Kim (Inha University) Dong Hyun Kim (Inha University) Ji-Eun Lee (Inha University) Soon Ki Kim (Inha University)
저널정보
대한혈액학회 Blood Research Blood Research Vol.51 No.4
발행연도
2016.1
수록면
268 - 273 (6page)

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BackgroundIn Korea, the prevalence of anemia and iron deficiency anemia (IDA) among older infants and young children remains high. To detect IDA early and to reduce its adverse impact, we assessed the characteristics of infants and young children who had IDA or were at risk of developing IDA, or who exhibited characteristics associated with severe anemia.MethodsAmong the 1,782 IDA-affected children aged 6 months to 18 years who visited the hospi-tal, we retrospectively analyzed the medical records and laboratory data of 1,330 IDA-af-fected children aged 6‒23 months who were diagnosed between 1996 and 2013. We ex-cluded patients with a C-reactive protein level ≥5 mg/dL.ResultsIDA was predominant in boys (2.14:1) during infancy and early childhood. The peak IDA incidence was noted among infants aged 9‒12 months. Only 7% patients exhibited symp-toms of IDA, while 23.6% patients with severe IDA demonstrated classic symptoms/signs of IDA. Low birth weight (LBW) infants with IDA demonstrated low adherence to iron supplementation. In a multivariate analysis, prolonged breastfeeding without iron for-tification (odds ratio [OR] 5.70), and a LBW (OR 6.49) were identified as risk factors of severe anemia.ConclusionLBW infants need more attention in order to increase their adherence to iron supple-mentation. For the early detection of IDA, nutritional status of all infants, and iron batteries of high-risk infants (LBW infants, infants with prolonged breastfeeding, picky eaters, and/or infants with the presence of IDA symptoms) should be evaluated at their health screening visits.

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