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논문 기본 정보

자료유형
학술저널
저자정보
Takashi Kobayashi (Akita Kousei Medical Center) Naohisa Miyakoshi (Akita University Graduate School of Medicine) Norikazu Konno (Akita Kousei Medical Center) Yoshinori Ishikawa (Akita University Graduate School of Medicine) Hideaki Noguchi (Akita University Graduate School of Medicine) Yoichi Shimada (Akita University Graduate School of Medicine)
저널정보
대한척추외과학회 Asian Spine Journal Asian Spine Journal Vol.12 No.6
발행연도
2018.1
수록면
1,117 - 1,122 (6page)

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Study Design: Prospective study. Purpose: To assess the prevalence of periodontoid calcification and its associations with acute cervical pain. Overview of Literature: Calcium pyrophosphate dihydrate (CPPD) deposition disease is a common rheumatological disorder that occurs especially in elderly patients. Although CPPD crystals induce acute arthritis, these crystals are not usually symptomatic. Calcification surrounding the odontoid process (periodontoid calcification) has been reported to induce inflammation, resulting in acute neck pain. This disease is called crowned dens syndrome. Whether calcification induces inflammation or whether the crystals are symptomatic remains unclear. Methods: The prevalence of periodontoid calcification at the atlas transverse ligament was examined by computed tomography of the upper cervical spine in patients suspected of brain disease but no cervical pain (control group, n=296), patients with pseudogout of the peripheral joints but no cervical pain (arthritis group, n=41), and patients with acute neck pain (neck pain group, n=22). Next, the correlation between the prevalence of periodontoid calcification and symptoms was analyzed. Results: In the control group, 40 patients (13.5%) showed periodontoid calcification with no significant difference in the prevalence with gender. The prevalence of calcification increased significantly with age (p =0.002). In the arthritis group, 26 patients (63.4%) reported periodontoid calcification. In the neck pain group, 14 patients (63.6%) reported periodontoid calcification. Multiple logistic regression analysis by age and group revealed that higher age, inclusion in the arthritis group, and inclusion in the neck pain group significantly affected the prevalence of calcification. Conclusions: Our results cumulatively suggest that periodontoid calcification is an aging-related reaction and that calcification per se does not always cause neck pain. Periodontoid calcification was observed more frequently in patients with pseudogout of the peripheral joints and in those with acute neck pain than in asymptomatic control patients.

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참고문헌 (14)

참고문헌 신청
Bouvet JP / 1985 / Acute neck pain due to calcifications surrounding the odontoid process : the crowned dens syndrome / Arthritis Rheum 28:1417~1420 google schola Goto S / 2007 / Crowned dens syndrome / J Bone Joint Surg Am 89:2732~2736 google schola Finckh A / 2004 / The cervical spine in calcium pyrophosphate dihydrate deposition disease : a prevalent casecontrol study / J Rheumatol 31:545~549 google schola Kobayashi T / 2014 / Acute neck pain caused by arthritis of the lateral atlantoaxial joint / Spine J 14:1909~1913 google schola Constantin A / 1996 / Calcification of the transverse ligament of the atlas in chondrocalcinosis : computed tomography study / Ann Rheum Dis 55:137~139 google schola

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