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학술저널
저자정보
Ji Yeon Seo (Healthcare System Gangnam Center Seoul National University Hospital) Seung Ho Choi (Healthcare System Gangnam Center Seoul National University Hospital) Jaeyoung Chun (Seoul National University College of Medicine) 이창현 (서울대학교병원) Ji Min Choi (Seoul National University College of Medicine) Eun Hyo Jin (Healthcare System Gangnam Center Seoul National University Hospital) Sung Wook Hwang (Seoul National University College of Medicine) Jong Pil Im (Seoul National University College of Medicine) 김상균 (Seoul National University College of Medicine) 김주성 (서울대학교)
저널정보
대한장연구학회 Intestinal research Intestinal research Vol.14 No.3
발행연도
2016.1
수록면
270 - 279 (10page)

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Background/Aims: The efficacy and safety of endoscopic resection of colorectal cancer derived from sessile serrated adenomasor traditional serrated adenomas are still unknown. The aims of this study were to verify the characteristics and outcomesof endoscopically resected early colorectal cancers developed from serrated polyps. Methods: Among patients who receivedendoscopic resection of early colorectal cancers from 2008 to 2011, cancers with documented pre-existing lesions were included. They were classified as adenoma, sessile serrated adenoma, or traditional serrated adenoma according to the baselinelesions. Clinical characteristics, pathologic diagnosis, and outcomes were reviewed. Results: Overall, 208 colorectal cancersdetected from 198 patients were included: 198 with adenoma, five with sessile serrated adenoma, and five with traditional serratedadenoma. The sessile serrated adenoma group had a higher prevalence of high-grade dysplasia (40.0% vs. 25.8%, P <0.001)than the adenoma group. During follow-up, local recurrence did not occur after endoscopic resection of early colorectal cancersdeveloped from serrated polyps. In contrast, two cases of metachronous recurrence were detected within a short follow-upperiod. Conclusions: Cautious observation and early endoscopic resection are recommended when colorectal cancer fromserrated polyp is suspected. Colorectal cancers from serrated polyp can be treated successfully with endoscopy.

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