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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 187 - 195 (9page)
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초록· 키워드
오류제보하기
Delayed arterial healing at culprit sites after drug-eluting stent (DES) placement for acute myocardial infarction (AMI) is associated with increased risk of late stent thrombosis. The Korea Acute Myocardial Infarction Registry was established in commemoration of the 50th anniversary of Korea Circulation Society. Between November 2005 and December 2016, more than 62,000 patients were registered from 50 primary percutaneous coronary intervention (PCI) centers in Korea. DES in AMI may be safe and effective, however, there is concern about increased stent thrombosis after DES implantation in AMI patients, requiring longer-term dual anti-platelet therapy to reduce the risk of late stent thrombosis. Device innovation is needed to overcome issues such as stent thrombosis and restenosis by using new coating materials with biocompatible polymers, different coating methods using non-polymer techniques, bioabsorbable stents and pro-healing stents. In this review article, we describe the current usage of DES in AMI in Korea and introduce novel DES uses in development for patients with AMI. We have developed many types of DES in our research laboratory. Abciximab-coated stents inhibited platelet thrombi and restenosis. Furthermore, anti-oxidants (carvedilol, probucol and alpha-lipoic acid) were used for stent coating. Currently we are developing novel DESs using polymer-free and natural binding techniques, peptide coating stents, gene-and-drug delivery, bioabsorbable stents using 3D printing, endothelial progenitor cell capturing stents to promote reendothelialization and reduce stent thrombosis. New DESs in development may be safe and effective in preventing late stent thrombosis and restenosis in patients with AMI.
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등록된 정보가 없습니다.
참고문헌 (40)
참고문헌 신청
Lee KH / 2011 / Benefit of early statin therapy in patients with acute myocardial infarction who have extremely low low-density lipoprotein cholesterol / J Am Coll Cardiol 58:1664~1671
Kim JH / 2016 / Multicenter cohort study of acute myocardial infarction in Korea-Interim analysis of the Korea acute myocardial infarction registry-national institutes of health registry / Circ J 80:1427~1436
Kook HY / 2014 / Current trend of acute myocardial infarction in Korea(from the Korea Acute Myocardial Infarction Registry from 2006 to 2013) / Am J Cardiol 114:1817~1822
Lee SR / 2008 / Clinical safety of drug-eluting stents in the Korea acute myocardial infarction registry / Circ J 72:392~398
Hong YJ / 2013 / The efficacy and safety of drug-eluting stents in patients with acute myocardial infarction : results from Korea Acute Myocardial Infarction(KAMIR) / Int J Cardiol 163:1~4
Kim JH / 2016 / Multicenter cohort study of acute myocardial infarction in Korea-Interim analysis of the Korea acute myocardial infarction registry-national institutes of health registry / Circ J 80:1427~1436
Kook HY / 2014 / Current trend of acute myocardial infarction in Korea(from the Korea Acute Myocardial Infarction Registry from 2006 to 2013) / Am J Cardiol 114:1817~1822
Lee SR / 2008 / Clinical safety of drug-eluting stents in the Korea acute myocardial infarction registry / Circ J 72:392~398
Hong YJ / 2013 / The efficacy and safety of drug-eluting stents in patients with acute myocardial infarction : results from Korea Acute Myocardial Infarction(KAMIR) / Int J Cardiol 163:1~4
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