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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 111 - 125 (15page)
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초록· 키워드
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Gene therapy holds a great promise and has been extensively investigated to improve bone formation and regeneration therapies in bone tissue engineering. A variety of osteogenic genes can be delivered by combining different vectors (viral or non-viral), scaffolds and delivery methodologies. Ex vivo & in vivo gene enhanced tissue engineering approaches have led to successful osteogenic differentiation and bone formation. In this article, we review recent advances of gene therapy-based bone tissue engineering discussing strengths and weaknesses of various strategies as well as general overview of gene therapy.
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참고문헌 (135)
참고문헌 신청
Ai-Aql ZS / 2008 / Molecular mechanisms controlling bone formation during fracture healing and distraction osteogenesis / J Dent Res 87:107~118
Lind M / 1996 / Growth factors: possible new clinical tools. A review / Acta Orthop Scand 67:407~417
Urist MR / 1965 / Bone: formation by autoinduction / Science 150:893~899
Sartori R / 2015 / BMPs and the muscle-bone connection / Bone 80:37~42
Friedlaender GE / 2001 / Osteogenic protein-1 (bone morphogenetic protein-7) in the treatment of tibial nonunions / J Bone Joint Surg Am 83-A(Suppl 1(Pt 2)):S151~S158
Lind M / 1996 / Growth factors: possible new clinical tools. A review / Acta Orthop Scand 67:407~417
Urist MR / 1965 / Bone: formation by autoinduction / Science 150:893~899
Sartori R / 2015 / BMPs and the muscle-bone connection / Bone 80:37~42
Friedlaender GE / 2001 / Osteogenic protein-1 (bone morphogenetic protein-7) in the treatment of tibial nonunions / J Bone Joint Surg Am 83-A(Suppl 1(Pt 2)):S151~S158
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