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- 대한상부위장관 헬리코박터학회 Korean Journal of Helicobacter Upper Gastrointestinal Research Korean Journal of Helicobacter Upper Gastrointestinal Research Vol.18 No.3
- 발행연도
- 2018.1
- 수록면
- 162 - 167 (6page)
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Cancer specimens obtained via surgical resection or biopsy are generally used to understand tumor-associated alterations; however, those approaches cannot always be performed because of their invasive nature, and they may fail to reflect current tumor dynamics and drug sensitivity, which may change during the therapeutic process. Therefore, many research groups have focused on developing a non-invasive biomarker with the ability to monitor tumor dynamics. Circulating tumor cells (CTCs) are metastatic cells released from the primary tumor into the bloodstream. Hematogenous spreading of CTCs is a crucial step in the metastatic cascade, which leads to the formation of overt metastases. CTCs have attracted considerable attention because of their easy accessibility and their superiority over conventional tumor markers. Detecting CTCs is considered a valuable modality to determine prognosis and monitor response to systemic therapies in patients with gastric cancer. Moreover, molecular analyses of CTCs may provide important biological information for individual patients with cancer, which may lead to the development of personalized cancer treatment. In this article, we review potential roles and clinical applications of CTCs in patients with gastric cancer. (Korean J Helicobacter Up Gastrointest Res 2018;18:-167)
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참고문헌 (40)
참고문헌 신청
정규원 / 2017 / Cancer Statistics in Korea: Incidence, Mortality, Survival, and Prevalence in 2014 / Cancer Research and Treatment 49(2):292~305
Nam SY / 2009 / Effect of repeated endoscopic screening on the incidence and treatment of gastric cancer in health screenees / Eur J Gastroenterol Hepatol 21:855~860
National Cancer Information Center / Common cancer sites in Korea
Hartgrink HH / 2009 / Gastric cancer / Lancet 374:477~490
Lim DH / 2004 / Patterns of failure in gastric carcinoma after D2 gastrectomy and chemoradiotherapy: a radiation oncologist's view / Br J Cancer 91:11~17
Nam SY / 2009 / Effect of repeated endoscopic screening on the incidence and treatment of gastric cancer in health screenees / Eur J Gastroenterol Hepatol 21:855~860
National Cancer Information Center / Common cancer sites in Korea
Hartgrink HH / 2009 / Gastric cancer / Lancet 374:477~490
Lim DH / 2004 / Patterns of failure in gastric carcinoma after D2 gastrectomy and chemoradiotherapy: a radiation oncologist's view / Br J Cancer 91:11~17
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