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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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A 46-year-old female with abnormal radiologic finding was diagnosed with pancreatic neuroendocrine tumor and multiple hepatic metastasis. Molecular targeted therapy (everolimus) and two times of transarterial chemoembolizations (TACE) were performed before pylorus-preserving pancreaticoduodenectomy (PPPD). After 2nd TACE and PPPD, grade 2 pancreatic neuroendocrine tumor was pathologically confirmed. Four times of additional TACE was done. After size increase of several probable hepatic metastasis in the both lobes of liver, laparoscopic left lateral sectionectomy of liver was performed. After two and half years of left lateral sectionectomy, 7th TACE was performed and the patients have survived without further disease progression. This case suggests that patients with pancreatic neuroendocrine tumor and hepatic metastasis can be treated by TACE, primary tumor resection, surgery for liver metastasis and molecular targeted therapy. Therefore, aggressive multidisciplinary approaches need to be considered for long term survival of patients with pancreatic neuroendocrine tumor with hepatic metastasis.
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참고문헌 (13)
참고문헌 신청
Yao JC / 2008 / One hundred years after “carcinoid”:epidemiology of and prognostic factors for neuroendocrine tumors in 35,825 cases in the United States / J Clin Oncol 26:3063~3072
장흥문 / 2011 / 진행성 췌장 신경내분비 종양에서의 일치된 치료 지침 / 대한내과학회지 80(4):393~396
Strosberg J / 2009 / Survival and prognostic factor analysis in patients with metastatic pancreatic endocrine carcinomas / Pancreas 38:255~258
Strosberg JR / 2011 / Prognostic validity of a novel American Joint Committee on Cancer Staging Classification for pancreatic neuroendocrine tumors / J Clin Oncol 29:3044~3049
Gupta S / 2003 / Hepatic artery embolization and chemoembolization for treatment of patients with metastatic carcinoid tumors: the MD Anderson experience / Cancer J 9:261~267
장흥문 / 2011 / 진행성 췌장 신경내분비 종양에서의 일치된 치료 지침 / 대한내과학회지 80(4):393~396
Strosberg J / 2009 / Survival and prognostic factor analysis in patients with metastatic pancreatic endocrine carcinomas / Pancreas 38:255~258
Strosberg JR / 2011 / Prognostic validity of a novel American Joint Committee on Cancer Staging Classification for pancreatic neuroendocrine tumors / J Clin Oncol 29:3044~3049
Gupta S / 2003 / Hepatic artery embolization and chemoembolization for treatment of patients with metastatic carcinoid tumors: the MD Anderson experience / Cancer J 9:261~267
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