지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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초록· 키워드
오류제보하기
Raynaud’s phenomenon (RP) is characterized by reversible digital vasospasm triggered by exposure to cold or emotional stress.
It manifests with unique ‘triphasic’ (pallor, cyanosis, erythema) or ‘biphasic’ (white, blue) color change. Clinically, RP is classified as primary RP, which does not have an underlying associated cause with a relatively benign course, and secondary RP, which predates various cause such as systemic connective tissue disease (CTD). Therefore, RP must be differentiated for detection of emerging CTD such as systemic sclerosis (SSc), systemic lupus erythematosus, and mixed conective tissue disease, ect. Nailfold capillaroscopy (NFC) is a non-invasive morphological study used routinely with antinuclear antibodies for parallel of secondary RP. A recent study showed NFC to be the best predictor of transition from a primary RP to secondary RP. The well-established role of NFC for early diagnosis of SSc, and potential for monitoring disease progression and predictive clinical complication makes NFC an important tool in research and clinical practice. In this paper, I present a recent update with emphasis on its possible role as a reliable diagnostic tool and biomarker in secondary RP.
목차
등록된 정보가 없습니다.
참고문헌 (27)
참고문헌 신청
Hong YS. / 2014 / Korean Colleage Rheumatology. Text book of rheumatology. 1st ed / Koonja :409~411
Suter LG. / 2005 / The incidence and natural history of Raynaud’s phenomenon in the community / Arthritis Rheum 52:1259~1263
Herrick AL. / 2012 / The pathogenesis, diagnosis and treatment of Raynaud phenomenon / Nat Rev Rheumatol 8:469~479
Cutolo M. / 2008 / Capillaroscopy / Best Pract Res Clin Rheumatol 22:1093~1108
Koenig M. / 2008 / Autoantibodies and microvascular damage are independent predictive factors for the progression of Raynaud’s phenomenon to systemic sclerosis : a twenty-year prospective study of 586 patients, with validation of proposed criteria for early systemic sclerosis / Arthritis Rheum 58:3902~3912
Suter LG. / 2005 / The incidence and natural history of Raynaud’s phenomenon in the community / Arthritis Rheum 52:1259~1263
Herrick AL. / 2012 / The pathogenesis, diagnosis and treatment of Raynaud phenomenon / Nat Rev Rheumatol 8:469~479
Cutolo M. / 2008 / Capillaroscopy / Best Pract Res Clin Rheumatol 22:1093~1108
Koenig M. / 2008 / Autoantibodies and microvascular damage are independent predictive factors for the progression of Raynaud’s phenomenon to systemic sclerosis : a twenty-year prospective study of 586 patients, with validation of proposed criteria for early systemic sclerosis / Arthritis Rheum 58:3902~3912
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