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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 66 - 73 (8page)
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This study analyzes the clinical characteristics of the brain metastasis (BM) of gynecologiccancer based on the type of cancer. In addition, the study examines the factors influencingthe survival. Total 61 BM patients of gynecologic cancer were analyzed retrospectivelyfrom January 2000 to December 2012 in terms of clinical and radiological characteristicsby using medical and radiological records from three university hospitals. There were 19(31.1%) uterine cancers, 32 (52.5%) ovarian cancers, and 10 (16.4%) cervical cancers. Themean interval to BM was 25.4 months (21.6 months in ovarian cancer, 27.8 months inuterine cancer, and 33.1 months in cervical cancer). The mean survival from BM was 16.7months (14.1 months in ovarian cancer, 23.3 months in uterine cancer, and 8.8 months incervical cancer). According to a multivariate analysis of factors influencing survival, typeof primary cancer, Karnofsky performance score, status of primary cancer, recursivepartitioning analysis class, and treatment modality, particularly combined therapies, weresignificantly related to the overall survival. These results suggest that, in addition totraditional prognostic factors in BM, multiple treatment methods such as neurosurgery andcombined chemoradiotherapy may play an important role in prolonging the survival forBM patients of gynecologic cancer.
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참고문헌 (36)
참고문헌 신청
Jemal A / 2002 / Cancer statistics, 2002 / CA Cancer J Clin 52:23~47
정규원 / 2012 / Cancer Statistics in Korea: Incidence, Mortality, Survival, and Prevalence in 2009 / Cancer Research and Treatment 44(1):11~24
Tangjitgamol S / 2004 / Role of surgical resection for lung, liver, and central nervous system metastases in patients with gynecological cancer: a literature review / Int J Gynecol Cancer 14:399~422
Nielsen SL / 1983 / Brain metastasis localized to an area of infarction / J Neurooncol 1:191~195
Wroński M / 1994 / Leiomyosarcoma of the uterus metastatic to brain : a case report and a review of the literature / Gynecol Oncol 54:237~241
정규원 / 2012 / Cancer Statistics in Korea: Incidence, Mortality, Survival, and Prevalence in 2009 / Cancer Research and Treatment 44(1):11~24
Tangjitgamol S / 2004 / Role of surgical resection for lung, liver, and central nervous system metastases in patients with gynecological cancer: a literature review / Int J Gynecol Cancer 14:399~422
Nielsen SL / 1983 / Brain metastasis localized to an area of infarction / J Neurooncol 1:191~195
Wroński M / 1994 / Leiomyosarcoma of the uterus metastatic to brain : a case report and a review of the literature / Gynecol Oncol 54:237~241
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