지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 1,604 - 1,611 (8page)
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Breast cancer is the most common type of female cancer. Tamoxifen, a selective estrogen receptor modulator, is widely used to decrease breast cancer recurrence and mortality among patients. However, it also increases the risk of endometrial cancer. This study aimed to assess knowledge and decisional conflict regarding tamoxifen use. Between June and October 2014, breast cancer patients using tamoxifen were consecutively screened and requested to complete a survey including the EQ-5D, Satisfaction with Decision Scale (SWD), Decisional Conflict Scale (DCS), and a self-developed, 15-item questionnaire measuring tamoxifen-related knowledge. The study sample comprised 299 patients. The mean total knowledge score was 63.4 of a possible 100.0 (range, 13.3-93.3). While 73.9% of the participants knew that tamoxifen reduces the risk of breast cancer recurrence, only 57.9% knew that the drug increases endometrial cancer risk. A higher education level (≥ college) was associated with a higher, total knowledge score (β = 4.291; P = 0.017). A higher knowledge score was associated with a decreased DCS score (β = -0.366; P < 0.001). A higher SWD score was also associated with decreased decisional conflict (β = -0.178; P < 0.001). In conclusion, the breast cancer patients with higher levels of tamoxifen-related knowledge showed lower levels of decisional conflict regarding tamoxifen use. Clinicians should provide the exact information about tamoxifen treatment to patients, based on knowledge assessment results, so as to aid patients’ decision-making with minimal conflict.
목차
등록된 정보가 없습니다.
참고문헌 (25)
참고문헌 신청
Siegel R / 2014 / Cancer statistics, 2014 / CA Cancer J Clin 64:9~29
정규원 / 2014 / Prediction of Cancer Incidence and Mortality in Korea, 2014 / Cancer Research and Treatment 46(2):123~130
Kesson EM / 2012 / Effects of multidisciplinary team working on breast cancer survival: retrospective, comparative, interventional cohort study of 13 722 women / BMJ 344:e2718
Burstein HJ / 2014 / Adjuvant endocrine therapy for women with hormone receptor-positive breast cancer : american society of clinical oncology clinical practice guideline focused update / J Clin Oncol 32:2255~2269
Fisher B / 1989 / A randomized clinical trial evaluating tamoxifen in the treatment of patients with node-negative breast cancer who have estrogen-receptor-positive tumors / N Engl J Med 320:479~484
정규원 / 2014 / Prediction of Cancer Incidence and Mortality in Korea, 2014 / Cancer Research and Treatment 46(2):123~130
Kesson EM / 2012 / Effects of multidisciplinary team working on breast cancer survival: retrospective, comparative, interventional cohort study of 13 722 women / BMJ 344:e2718
Burstein HJ / 2014 / Adjuvant endocrine therapy for women with hormone receptor-positive breast cancer : american society of clinical oncology clinical practice guideline focused update / J Clin Oncol 32:2255~2269
Fisher B / 1989 / A randomized clinical trial evaluating tamoxifen in the treatment of patients with node-negative breast cancer who have estrogen-receptor-positive tumors / N Engl J Med 320:479~484
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