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자료유형
학술저널
저자정보
저널정보
대한비뇨기과학회 Investigative and Clinical Urology Investigative and Clinical Urology Vol.56 No.2
발행연도
2015.1
수록면
125 - 130 (6page)

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Purpose: To report on lessons learnt in the management of primary invasive penile cancer in a major tertiary hospital in Australia. Materials and Methods: Medical records for all patients who underwent surgery for primary invasive penile cancer betweenJanuary 2000 and January 2011 were obtained. Patient demographics, clinical status of inguinal node, cancer stage and clinicaloutcomes were reviewed. All patients were followed up for a minimum of 48 months postoperative unless patient deceased withinthe first 48 months from the time of penile cancer surgery. Results: Over the 11-year period, a total of 23 cases of invasive penile cancer were identified. Partial penectomy was the mostcommon form of organ preserving surgery and the majority of patients have pT1b disease. Of the 9 patients with clinically palpableinguinal nodes, 7 patients were diagnosed with pN3 disease following inguinal lymphadenectomy. The Kaplan-Meier cancerspecificsurvival at 72 months showed decreasing survival based on tumour stage (83% in pT1, 79% in pT2, and 64% in pT3 disease)and nodal disease (100% in node negative, 50% in superficial inguinal lymphadenopathy, and 38% in patients with deep inguinaland/or pelvic lymphadenopathy) (p=0.082). The Kaplan-Meier cancer-specific survival revealed statistically significant difference insurvival outcome in patients with local recurrence vs. systemic metastasis disease (33% vs. 17%, p=0.008). Conclusions: The presence of high risk features such as tumour stage, lymph node involvement and distant metastasis carries asignificant higher risk of death and tumour recurrence in patients with penile cancer and inguinal lymph node metastasis.

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