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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 44 - 50 (7page)
이용수
초록· 키워드
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Background and Objectives: To investigate the impact of age on arterial stiffness and blood pressure (BP) variables in newly diagnoseduntreated hypertension (HT).
Subjects and Methods: A total of 144 patients with newly diagnosed untreated HT were divided into two groups: young group (age≤50 years, n=71), and old group (age >50 years, n=73). BP variables were measured on office or 24 hours ambulatory BP monitoring(ABPM). Parameters of arterial stiffness were measured on pulse wave velocity (PWV). Pulse wave analysis (PWA) was compared.
Results: Although office BP and pulse pressure (PP) were significantly (p<0.05) higher in the young group than in the old group, BP and PPon ABPM were not significantly different. Central systolic BP and PP, augmentation pressure, augmentation index on PWA, and PWV weresignificantly higher or faster in the old group compared to that in the young group. Age showed significant positive correlation with bothPWV and PWA variables in the young group with HT. However, age only showed significant positive correlation with PWV in the old groupwith HT. In the young group with HT, PWA variable showed better correlation with age than PWV.
Conclusion: Considering BP levels on ABPM, office BP is prone to be overestimated in young patients with HT. Parameters of arterial stiffnessmeasured by PWV and PWA were more affected by age rather than by BP level in patients with HT. Therefore, PWA variable might be amore sensitive marker of arterial stiffness in young patients with HT. However, PWV might be a better marker for old patients with HT.
목차
등록된 정보가 없습니다.
참고문헌 (28)
참고문헌 신청
Rutan GH / 1988 / Mortality associated with diastolic hypertension and isolated systolic hypertension among men screened for the Multiple Risk Factor Intervention Trial / Circulation 77:504~514
Turnbull F / 2003 / Blood Pressure Lowering Treatment Trialists’ Collaboration. Effects of different blood-pressure-lowering regimens on major cardiovascular events: results of prospectively-designed overviews of randomised trials / Lancet 362:1527~1535
McManus RJ / 2012 / National Institute for Health and Clinical Excellence. NICE hypertension guideline 2011: evidence based evolution / BMJ 344:e181
Staessen JA / 1997 / Nocturnal blood pressure fall on ambulatory monitoring in a large international database. The “Ad Hoc’ Working Group / Hypertension 29(1 Pt 1):30~39
Phillips RA / 2001 / Dipping is superior to cusums analysis in assessment of the risk of stroke in a case-control study / Am J Hypertens 14(7 Pt 1):649~652
Turnbull F / 2003 / Blood Pressure Lowering Treatment Trialists’ Collaboration. Effects of different blood-pressure-lowering regimens on major cardiovascular events: results of prospectively-designed overviews of randomised trials / Lancet 362:1527~1535
McManus RJ / 2012 / National Institute for Health and Clinical Excellence. NICE hypertension guideline 2011: evidence based evolution / BMJ 344:e181
Staessen JA / 1997 / Nocturnal blood pressure fall on ambulatory monitoring in a large international database. The “Ad Hoc’ Working Group / Hypertension 29(1 Pt 1):30~39
Phillips RA / 2001 / Dipping is superior to cusums analysis in assessment of the risk of stroke in a case-control study / Am J Hypertens 14(7 Pt 1):649~652
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