지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
Background: Serum ferritin is well known as a marker that is reflective of the iron storage status in blood.
But only the hemoglobin level is generally included in the current selection criteria for blood donors. Recent studies have continuously shown that the serum ferritin levels are lower for the blood donors, and especially for women and repeat donors with a normal hemoglobin level. It has been suggested that serum ferritin should be included in the blood donor selection criteria. In this study, we examined the serum ferritin status in a Korean population, and we checked the validity of the recent related studies.
Methods: The hemoglobin and serum ferritin levels of the blood donors who visited Seoul National University Bundang Hospital were measured (total donors: 353, males: 252, females: 101). The hemoglobin levels were evaluated according to gender and the serum ferritin level, and the changes in the serum ferritin level were also checked for the repeat donors.
Results: The median serum ferritin level was 89.7 ng/mL (2.5∼97.5%, 13.0∼280.7 ng/mL). As classified by the serum ferritin levels, 9.9% of the males and 38.6% of the females showed low serum ferritin (≤30 ng/mL)with a normal hemoglobin level. Among the 33 cases of repeat donors, 25 cases showed reduced serum ferritin changes (mean change: 17.4%).
Conclusion: Similar to other recent studies, we found that the donors with normal hemoglobin could show a low serum ferritin level and especially the women and repeat donors in a Korean population. For the blood donors’ safety, it is time to consider that the serum ferritin level should be included in the criteria for blood donor selection.
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참고문헌 (21)
참고문헌 신청
Knovich MA / 2009 / Ferritin for the clinician / Blood Rev 23:95~104
Hallberg L / 1993 / Screening for iron deficiency: an analysis based on bone-marrow examinations and serum ferritin determinations in a population sample of women / Br J Haematol 85:787~798
Pasricha SR / 2011 / Hemoglobin and iron indices in nonanemic premenopausal blood donors predict future deferral from whole blood donation / Transfusion
WHO / 2004 / Assessing the iron status of populations: report of a joint World Health Organization/Centers for Disease Control and Prevention technical consultation on the assessment of iron status at the population level
WHO / 2001 / Iron deficiency anaemia: assessment, prevention, and control. A guide for programme managers / World Health Organization
Hallberg L / 1993 / Screening for iron deficiency: an analysis based on bone-marrow examinations and serum ferritin determinations in a population sample of women / Br J Haematol 85:787~798
Pasricha SR / 2011 / Hemoglobin and iron indices in nonanemic premenopausal blood donors predict future deferral from whole blood donation / Transfusion
WHO / 2004 / Assessing the iron status of populations: report of a joint World Health Organization/Centers for Disease Control and Prevention technical consultation on the assessment of iron status at the population level
WHO / 2001 / Iron deficiency anaemia: assessment, prevention, and control. A guide for programme managers / World Health Organization
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