지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2005.1
- 수록면
- 53 - 62 (10page)
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초록· 키워드
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The presence of the apolipoprotein E4 genotype is reported to be associated with the increased risked of dementia. Therefore, we hypothesized that the Apo E4 genotype has low physical fitness and high serum cholesterol. We determined the Apo E genotype using a polymerase chain reaction(PCR) with Hha I restriction fragment length polymorphism(RFLP), in a DNA sample of 14 elderly women aged 78.67±3.37yrs. The genetic subtype was classified by its digestion patterns e.g. E3, E4, and body composition, physical fitness and serum lipids were compared both genotype. The body composition and physical fitness were not different according to genotype. But HDL-C and Apo A1 concentrations of E3 genotype were significantly higher compared to the E4 genotype. There results suggest that body composition and physical fitness are not related the Apo E gene but it may affect serum lipids.
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