지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2006.1
- 수록면
- 301 - 310 (10page)
이용수
초록· 키워드
오류제보하기
As about 90% of all diabetic patients is consisted of Non-Insulin Dependent Diabetes Mellitus (NIDDM, type II diabetes), it is important to study how insulin's ability is decreased and how insulin action can be improved in these patient as well as in healthy people. Insulin resistance, one of the most prominent metabolic symptoms in type II diabetes, is a condition in which insulin action is lower than normal, an increase in insulin action is the most critical factor to maintain normal blood glucose level in type II diabetic population. One way to improve insulin action is exercise (or muscle contraction). There is an evidence that 5'AMP-Activated Protein Kinase (AMPK) and glycogen concentration might be associated with skeletal muscle insulin sensitivity. These two factors are influenced by exercise or muscle contraction such that activity of AMPK is increased, and glycogen is utilized and its concentration is decreased by muscular activity. Thus, an increase in AMPK activity and decrease in glycogen concentration may affect insulin sensitivity in skeletal muscle. However, the exact cellular mechanism by which these two factors are associated with muscle insulin sensitivity is not known. Furthermore, how insulin signaling pathway post exercise can be altered to increase insulin action is still not known.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청이 논문의 저자 정보
최근 본 자료
댓글(0)
0