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논문 기본 정보

자료유형
학술저널
저자정보
Yuan Yee Lee (Kyungpook National University) Sung Dae Kim (Kyungpook National University) Seung-Chun Park (Kyungpook National University) Man Hee Rhee (Kyungpook National University)
저널정보
고려인삼학회 Journal of Ginseng Research Journal of Ginseng Research Vol.46 No.1
발행연도
2022.1
수록면
54 - 61 (8page)

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초록· 키워드

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Ginseng has been widely studied due to its various therapeutic properties on various diseases such as cardiovascular disease (CVD). Cardiovascular disease has been canonically known to be caused by high levels of low-density lipoproteins (LDL) in the bloodstream, in addition to the impaired vasodilatory effects of cholesterol. However, current research on CVD has revealed a cascade of mechanisms involving a series of events that contribute to the progression of CVD. Although this has been elucidated and summarized in previous studies the detailed correlation between platelet aggregation and innate immunity that plays an important role in CVD progression has not been thoroughly summarized. Furthermore, immune cell subtypes also contribute to the progression of plaque formation in the subendothelial layer. Thrombus formation and the coagulation cascade also have a vital role in the progression of atherosclerosis. Hence, in this mini review we aim to elucidate, summarize, and propose the potent therapeutic effect of ginseng on CVD, mainly on platelet aggregation, plaque formation, and thrombus formation.

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ABSTRACT
1. Introduction
2. Activation of the inflammatory cascade in the subendothelial layer
3. Ginseng for atherosclerosis therapeutics
4. Future perspectives and research direction
References

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