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Clinical safety and efficacy of a novel marine source of the long -chain omega-3 fatty acids
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Type
Academic journal
Author
Joung-Hyun Park (Marine Bioprocess) Kathy Musa-Veloso (Intertek Cantox) Ho-Seok Ji
Journal
The Korean Society for Marine Biotechnology Journal of Marine Bioscience and Biotechnology Vol.14 No.1 KCI Accredited Journals
Published
2022.6
Pages
43 - 50 (8page)

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Clinical safety and efficacy of a novel marine source of the long -chain omega-3 fatty acids
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Squid is a sustainable source of long-chain omega 3 fatty acids. This study aims to assess the safety and triglyceride-lowering efficacy of refined oil derived from the squid(Todarodes pacificus) viscera. Male and female participants with elevated fasting serum lipids (i.e., total cholesterol of ≥5.2 mmol/L or fasting serum triglyceride of ≥1.65 mmol/L) were randomly allocated to the control (n = 52) or squid oil group (n = 52), and participants in the latter group were instructed to consume 3 g of squid oil daily for 60 days. None of the subjects reported adverse events associated with the consumption of squid oil. Baseline clinical chemistry and hematological parameter values and those toward the end of the treatment period were similar, and all values were within the normal range. Fasting cholesterol and triglyceride levels in the control and squid oil groups were similar; however, toward the end of the 60 day study period, these levels significantly reduced in the squid oil group relative to those in the control group (P< 0.01). However, high-density lipoprotein-cholesterol remained unchanged in both groups. Thus, it can be inferred that squid oil is a safe source of long-chain omega-3 fatty acids and has beneficial effects on the blood lipid levels. This is the first clinical study on squid oil usage, and suggests that it could be a sustainable source of omega 3 fatty acids.
#squid oil #eicosapentaenoic acid #docosahexaenoic acid #triglycerides

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