지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한외과학회 Annals of Surgical Treatment and Research Annals of Surgical Treatment and Research Vol.102 No.4
- 발행연도
- 2022.4
- 수록면
- 177 - 184 (8page)
이용수
초록· 키워드
오류제보하기
Purpose: A seroma is a collection of exudates after surgical trauma in wound healing. Fibrin glue is used to prevent seroma by reducing the generation of exudate. However, the impact of fibrin glue on the prevention of seroma remains debatable. Therefore, we conducted a randomized controlled pilot trial to investigate the effect of the amount of fibrin glue used on the generation of exudate after thyroidectomy and the sample size of future definitive trials.
Methods: Between February and December 2020, 41 patients were enrolled; 21 patients in the low fibrin group and 20 in the high fibrin group. Stratified randomization was performed based on sex, body mass index, and thyroiditis. All patients underwent total thyroidectomy and bilateral central compartment dissection. In the low and high fibrin groups, 2 mL and 6 mL of fibrin glue were applied to patients, respectively.
Results: Both the total drain volume and flow rate during the first 12 hours were lower in the high fibrin group than in the low fibrin group (65.0 mL vs. 47.6 mL, P = 0.008 and 2.7 mL/hr vs. 1.8 mL/hr, P = 0.002, respectively). The calculated sample size for future randomized controlled trial was 32 patients (α = 0.05, power = 0.8), and the power of this trial was 0.91 with μ₁ = 2.7, μ₂ = 1.8, σ = 0.9, and α = 0.05 (μ = mean, σ = standard deviation).
Conclusion: Six milliliters of fibrin glue could reduce total drain volume and flow rate of exudate after thyroidectomy. Therefore, applying an appropriate amount of fibrin glue after thyroidectomy may reduce postoperative seroma.
Methods: Between February and December 2020, 41 patients were enrolled; 21 patients in the low fibrin group and 20 in the high fibrin group. Stratified randomization was performed based on sex, body mass index, and thyroiditis. All patients underwent total thyroidectomy and bilateral central compartment dissection. In the low and high fibrin groups, 2 mL and 6 mL of fibrin glue were applied to patients, respectively.
Results: Both the total drain volume and flow rate during the first 12 hours were lower in the high fibrin group than in the low fibrin group (65.0 mL vs. 47.6 mL, P = 0.008 and 2.7 mL/hr vs. 1.8 mL/hr, P = 0.002, respectively). The calculated sample size for future randomized controlled trial was 32 patients (α = 0.05, power = 0.8), and the power of this trial was 0.91 with μ₁ = 2.7, μ₂ = 1.8, σ = 0.9, and α = 0.05 (μ = mean, σ = standard deviation).
Conclusion: Six milliliters of fibrin glue could reduce total drain volume and flow rate of exudate after thyroidectomy. Therefore, applying an appropriate amount of fibrin glue after thyroidectomy may reduce postoperative seroma.
목차
INTRODUCTION
METHODS
RESULTS
DISCUSSION
REFERENCES
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
The Effect of Fibrin Glue on the Quantity of Drainage after Thyroidectomy: A Randomized Controlled Study
대한외과학회 학술대회 초록집
2021 .11
-
Glue-Sniffing Neuropathy: A Case Report
대한근전도 전기진단의학회지
2024 .04
-
Treatment for a Post-Reconstruction Seroma Using Viscum album Extract in a Patient with a Pressure Ulcer: A Case Series
Journal of Wound Management and Research
2022 .02
-
Survey Results Compare Transoral Thyroidectomy to Open Thyroidectomy
대한외과학회 학술대회 초록집
2022 .11
-
Biomimetic Tissue Glues for Post Surgical Applications
대한외과학회 학술대회 초록집
2021 .11
-
Fibrin glue-infiltrating hemostasis for intractable bleeding from the liver or spleen during liver transplantation
Annals of Hepato-Biliary-Pancreatic Surgery
2016 .11
-
Determination of Patient Learning Needs after Thyroidectomy
Asian Pacific journal of cancer prevention : APJCP
2016 .01
-
Fascia Suture Technique Is a Simple Approach to Reduce Postmastectomy Seroma Formation
Journal of Breast Cancer
2020 .01
-
Risk of Suicide Attempt after Thyroidectomy: A Nationwide Population Study in South Korea
PSYCHIATRY INVESTIGATION
2021 .01
-
Effect of Collagen-Enhanced Fibrin Sealant on Seroma Formation in a Rat Mastectomy Model
Journal of Wound Management and Research
2020 .01
-
양측 액와유륜부 접근법을 이용한 무배액관 로봇 또는 내시경하 갑상선 절제술의 안정성에 대한 예비연구: 다기관 연구
The Journal of Endocrine Surgery
2015 .01
-
Transaxillary Endoscopic Thyroidectomy versus Conventional Open Thyroidectomy for Papillary Thyroid Cancer: 5-year Surgical Outcomes
The Journal of Endocrine Surgery
2016 .01
-
2 cm 이하의 저위험군 갑상선유두암 환자에서 갑상선엽절제술과 갑상선전절제술의 비교연구
International Journal of Thyroidology
2019 .01
-
A New Glue to Replace the Tacker
대한외과학회 학술대회 초록집
2023 .05
-
Nationwide Multicenter Survey for Current Status of Endoscopic Thyroidectomy in Korea
Clinical and Experimental Otorhinolaryngology
2015 .01
-
Analysis of Initial Experience of Robotic Bilateral Axillo-Breast Approach Thyroidectomy For 30 Months
The Journal of Endocrine Surgery
2023 .06
-
Two-Stage Thyroidectomy Driven by Intraoperative Neuromonitoring: Informed Consent Process and Its Effect on Patient Willingness and Consent Rates
The Journal of Endocrine Surgery
2020 .01
-
Surgical Completeness of Robotic Thyroidectomy Using the Bilateral Axillo-Breast Approach : Comparison with Open Conventional Thyroidectomy
대한임상종양학회 학술대회지
2015 .02
-
A Simple, Reliable, and Inexpensive Method for Seroma Drainage
Archives of plastic surgery : APS
2015 .01
-
Comparative study of the prevention of seroma formation in immediate breast reconstruction with latissimus dorsi myocutaneous flaps
Archives of Aesthetic Plastic Surgery
2020 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0
UCI(KEPA) : I410-ECN-0101-2023-514-000221400