지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2022.3
- 수록면
- 143 - 149 (7page)
이용수
초록· 키워드
오류제보하기
Background and Objectives Previous studies reported abnormalities in MRI as a poorprognostic indicator of sudden sensorineural hearing loss (SSNHL). Since abnormalities inthree-dimensional (3D) fluid-attenuated inversion recovery (FLAIR) are strongly correlatedwith the initial hearing function, the prognostic value of the 3D FLAIR images should becarefully evaluated to avoid collinearity. We aimed to evaluate abnormalities on the 3DFLAIR images as an independent prognostic factor in the matched SSNHL groups.
Subjects and Method We retrospectively reviewed medical records of 179 patients withSSNHL who underwent temporal MRI, including the 3D FLAIR sequence, between January2015 and December 2019. Patients were divided based on the presence of cochlear abnormalitieson the 3D FLAIR images. Hearing prognosis was evaluated with and without matchingfor initial hearing and treatment interval.
Results The groups were similar in sex (p=0.091), age (p=0.925), treatment interval (p=0.216), and MRI interval (p=0.828). Notably, patients with cochlear abnormalities on the 3DFLAIR images showed distinctly more severe hearing loss (p<0.001) at the initial pure toneaverage (PTA) assessment and poorer outcomes (p<0.001) compared to those without abnormality.
After matching for initial hearing and treatment interval, the hearing outcome, measuredby PTA, was similar between the groups (p=0.681).
Conclusion Cochlear signal abnormality in 3D FLAIR MRI was associated with poor initialhearing. However, it did not affect hearing recovery outcomes when the groups werematched.
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