Analysis Between Kidney Function and Hearing Loss Using Hemodynamic and Physical Characteristics: A Large Cross-Sectional Cohort Study With Health Screening Test

김상현; 김민범; 김태환; 이미연; 이정엽; 홍준표; 장선오; 이상혁

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자료유형: 학술저널

저자정보: 김상현 (성균관대학교 의과대학 강북삼성병원 이비인후과학교실) 김민범 (성균관대학교 의과대학 강북삼성병원 이비인후과학교실) 김태환 (성균관대학교 의과대학 강북삼성병원 이비인후과학교실) 이미연 (성균관대학교 의과대학 강북삼성병원 연구개발경영학과 생물통계학부) 이정엽 (성균관대학교 의과대학 강북삼성병원 이비인후과학교실) 홍준표 (성균관대학교 의과대학 강북삼성병원 이비인후과학교실) 장선오 (성균관대학교 의과대학 강북삼성병원 이비인후과학교실) 이상혁 (성균관대학교 의과대학 강북삼성병원 이비인후과학교실)

저널정보: 대한이비인후과학회 대한이비인후-두경부외과학회지 대한이비인후-두경부외과학회지 제65권 제10호

발행연도: 2022.10

수록면: 587 - 593 (7page)

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Background and Objectives A large-scale community-based study of the general populationhas not been conducted. There have been no studies on the relationship between decreasedrenal function and the degree of hearing loss. Thus, the purpose was to evaluate the relationshipbetween hearing loss and impaired renal function with a large number of populations. Subjects and Method We performed a cross-sectional population-based cohort study byenrolling 470718 adults, 18 to 80 years old with pure tone audiometry tests who had regularhealth screening between 2013 and 2018. Hearing loss was defined as a pure-tone average ofthresholds at 500, 1000, and 2000 Hz in both right and left ears. Kidney function was evaluatedbased on eGFR. Chronic kidney disease (CKD) was diagnosed as an eGFR<60 mL/min/1.73 m². Other predictor variables including noise and age that can affect hearing werealso used to evaluate correlation factors. Results Of Participants with CKD, 14.2% had any hearing loss (>25 dB) and 5.0% had abovemoderate hearing loss (>40 dB). But those with normal kidney function, 2.0% either had anyhearing loss and 0.4% had above moderate hearing loss. The odds ratio (OR) of above moderatehearing loss for participants with CKD was 1.51 (95% confidence interval [CI]: 1.15-2.00,p=0.003) but the OR of mild hearing loss for participants with CKD was 0.82 (95% CI: 0.67-1.02, p=0.073). The result suggested that CKD and above moderate hearing loss were relatedeven after correcting for potential confounders, but had no statistical significance with mildhearing loss.

#Chronic kidney insufficiency #Glomerular filtration rate #Hearing loss #Kidney.

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