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논문 기본 정보

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저자정보
Min Jinsoo (Division of Pulmonary and Critical Care Medicine Department of Internal Medicine Seoul St. Mary’s H) Kim Hyung Woo (Division of Pulmonary and Critical Care Medicine Department of Internal Medicine Incheon St. Mary’s) Choi Joon Young (Division of Pulmonary and Critical Care Medicine Department of Internal Medicine Incheon St. Mary’s) Shin Ah Young (Division of Pulmonary and Critical Care Medicine Department of Internal Medicine Incheon St. Mary’s) Kang Ji Young (Division of Pulmonary and Critical Care Medicine Department of Internal Medicine Seoul St. Mary’s H) Lee Yunhee (Department of Urology Seoul St. Mary’s Hospital College of Medicine The Catholic University of Kore) Myong Jun-Pyo (Department of Occupational and Environmental Medicine Seoul St. Mary’s Hospital College of Medicine) Jeong Hyunsuk (Department of Preventive Medicine College of Medicine The Catholic University of Korea Seoul Korea.) Bae Sanghyuk (Department of Preventive Medicine College of Medicine The Catholic University of Korea Seoul Korea.) Koo Hyeon-Kyoung (Division of Pulmonary and Critical Care Medicine Department of Internal Medicine Ilsan Paik Hospita) Lee Sung-Soon (Division of Pulmonary and Critical Care Medicine Department of Internal Medicine Ilsan Paik Hospita) Park Jae Seuk (Division of Pulmonary Medicine Department of Internal Medicine Dankook University College of Medici) Yim Hyeon Woo (Department of Preventive Medicine College of Medicine The Catholic University of Korea Seoul Korea.) Kim Ju Sang (Division of Pulmonary and Critical Care Medicine Department of Internal Medicine Incheon St. Mary’s)
저널정보
대한의학회 Journal of Korean Medical Science Journal of Korean Medical Science Vol.37 No.20
발행연도
2022.5
수록면
1 - 13 (13page)
DOI
10.3346/jkms.2022.37.e164

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Background: In 2017, Korea implemented nationwide latent tuberculosis infection (LTBI) project targeting healthcare workers (HCWs). We aimed to assess its performance using the cascade of care model. Methods: We included 45,503 employees of medical institutions with positive interferongamma release assay result who participated between March 2017 and December 2018. We described percentages of LTBI participants completing each step in the cascade of care. Poisson regression model was conducted to assess individual characteristics and factors associated with not-visiting clinics for further care, not-initiating LTBI treatment, and notcompleting treatment. Results: Proportions of visiting clinics and initiating and completing treatment in HCWs were 54.9%, 38.5%, and 32.0%, respectively. Despite of less likelihood of visiting clinics and initiating LTBI treatment, older age ≥ 65 years were more likely to complete treatment (adjusted relative risk [aRR], 0.80; 95% confidence interval [CI], 0.64?0.99), compared to young age < 35 years. Compared to nurses, doctors were less likely to visit clinic; however, were more likely to initiate treatment (aRR, 0.88; 95% CI, 0.81?0.96). Those who visited public health centers were associated with not-initiating treatment (aRR, 1.34; 95% CI, 1.29?1.40). When treated at private hospitals, 9-month isoniazid monotherapy was less likely to complete treatment, compared to 3-month isoniazid and rifampicin combination therapy (aRR, 1.33; 95% CI, 1.16?1.53). Conclusion: Among employees of medical institutions with LTBI, only one third completed treatment. Age, occupation, treatment center, and initial regimen were significantly related to LTBI treatment performance indicators. Rifampicin-based short treatment regimens were effective under standard of care.
#Latent TB #Preventive Therapy #Quality Control #Doctor #Nurse

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