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논문 기본 정보

자료유형
학술저널
저자정보
Kang Seokin (Department of Gastroenterology Asan Medical Center University of Ulsan College of Medicine Seoul Ko) Kim Do Hoon (Department of Gastroenterology Asan Medical Center University of Ulsan College of Medicine Seoul Ko) Kim Yuri (Department of Gastroenterology Asan Medical Center University of Ulsan College of Medicine Seoul Ko) Jeon Dongsub (Department of Gastroenterology Asan Medical Center University of Ulsan College of Medicine Seoul Ko) Na Hee Kyong (Department of Gastroenterology Asan Medical Center University of Ulsan College of Medicine Seoul Ko) Lee Jeong Hoon (Department of Gastroenterology Asan Medical Center University of Ulsan College of Medicine Seoul Ko) Ahn Ji Yong (Department of Gastroenterology Asan Medical Center University of Ulsan College of Medicine Seoul Ko) Jung Kee Wook (Department of Gastroenterology Asan Medical Center University of Ulsan College of Medicine Seoul Ko) Choi Kee Don (Department of Gastroenterology Asan Medical Center University of Ulsan College of Medicine Seoul Ko) Song Ho June (Department of Gastroenterology Asan Medical Center University of Ulsan College of Medicine Seoul Ko) Lee Gin Hyug (Department of Gastroenterology Asan Medical Center University of Ulsan College of Medicine Seoul Ko) Jung Hwoon-Yong (Department of Gastroenterology Asan Medical Center University of Ulsan College of Medicine Seoul Ko)
저널정보
대한의학회 Journal of Korean Medical Science Journal of Korean Medical Science Vol.37 No.23
발행연도
2022.6
수록면
1 - 10 (10page)
DOI
10.3346/jkms.2022.37.e184

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초록· 키워드

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Background: No definite guidelines for the management of small esophageal subepithelial tumors (SETs) have been established, because there are limited data and studies on their natural history. We aimed to assess the natural history and propose optimal management strategies for small esophageal SETs. Methods: Patients diagnosed as esophageal SETs ≤ 30 mm in size between 2003 and 2017 using endoscopic ultrasound (EUS) with a minimal follow-up of 3 months were enrolled, and their esophagogastroduodenoscopy (EGD) and EUS were retrospectively reviewed. Results: Of 275 esophageal SETs in 262 patients, the initial size was < 10 mm, 10?20 mm, and 20?30 mm in 104 (37.8%), 105 (38.2%), and 66 (24.0%) lesions, respectively. Only 22 (8.0%) SETs showed significant changes in size and/or echogenicity and/or morphology at a median of 40 months (range, 4?120 months). Tissues of 6 SETs showing interval changes were obtained using EUS-guided fine needle aspiration biopsy; 1 was identified as a gastrointestinal stromal tumor (GIST) and was surgically resected, while the other 5 were leiomyomas and were regularly observed. Eight SETs showing interval changes were resected surgically or endoscopically without pathological confirmation; 1 was a GIST, 2 were granular cell tumors, and the other 5 were leiomyomas. Conclusion: Regular follow-up with EGD or EUS may be necessary for esophageal SETs ≤ 30 mm in size considering that small portion of them has a possibility of malignant potential. When esophageal SETs ≤ 30 mm show significant interval changes, pathological confirmation may precede treatment to avoid unnecessary resection.

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