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자료유형
학술저널
저자정보
Kim Dai Hyun (Department of Dermatology Korea University College of Medicine Seoul Korea.Department of Anatomy Ko) Cho Jun Hyuk (Department of Dermatology Korea University College of Medicine Seoul Korea.) Park Sung Jin (Department of Dermatology Korea University College of Medicine Seoul Korea.) Seo Soo Hong (Department of Dermatology Korea University College of Medicine Seoul Korea.) Ahn Hyo Hyun (Department of Dermatology Korea University College of Medicine Seoul Korea.)
저널정보
대한의학회 Journal of Korean Medical Science Journal of Korean Medical Science Vol.37 No.24
발행연도
2022.6
수록면
1 - 9 (9page)
DOI
10.3346/jkms.2022.37.e190

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Background: Pityriasis rosea (PR) is a papulosquamous eruption with generally unknown origin but suspected to be related to viral etiologies. The clinicopathological spectrum of several disorders with viral etiologies has been altered after the coronavirus disease 2019 (COVID-19) pandemic. The author group could experience coherent histological alterations in PR after the COVID-19 pandemic. This study aimed to investigate how the clinicopathological findings of PR were changed after the COVID-19 pandemic. Methods: Patients (n = 11) diagnosed with PR based on the clinical manifestations and skin biopsies between February 2018 and October 2019 and 11 patients in February 2020 and October 2021 were retrospectively analyzed by investigating the medical records. Results: The patients with PR during the COVID-19 pandemic demonstrated statistically significant histopathological alterations from classic brisk and dense infiltration pattern to dormant and sparse infiltration and psoriasiform-dominant patterns (P = 0.019). PR was associated with more frequent pruritus during the pandemic period (P = 0.027). Conclusion: In conclusion, PR demonstrated a significant histopathological alteration with more frequent pruritus during the COVID-19 pandemic. The comparative results about clinicopathological findings of PR will provide a useful reference for dermatologists in the diagnostic process of PR in the COVID-19 pandemic.

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