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논문 기본 정보

자료유형
학술저널
저자정보
Chung Youseung (Division of Infectious Diseases Department of Internal Medicine Korea University College of Medicin) Kim Eun Jin (Division of Infectious Diseases Department of Internal Medicine Ajou University School of Medicine) Kim Hee-Sung (Department of Internal Medicine Chungbuk National University College of Medicine Cheongju Korea.) Park Kyung-Hwa (Department of Infectious Diseases Chonnam National University Medical School Gwangju Korea.) Baek Ji Hyeon (Division of Infectious Diseases Department of Internal Medicine Inha University College of Medicine) Kim Jungok (Department of Internal Medicine Chungnam National University School of Medicine Daejeon Korea.Divis) Lee Ji Yeon (Department of Infectious Diseases Keimyung University Dongsan Hospital Keimyung University School o) Lee Chang-Seop (Department of Internal Medicine Jeonbuk National University Medical School Jeonju Korea.) Lim Seungjin (Division of Infectious Diseases Department of Internal Medicine Pusan National University Yangsan H) Kim Shin-Woo (Department of Internal Medicine School of Medicine Kyungpook National University Daegu Korea.) Kim Eu Suk (Division of Infectious Diseases Department of Internal Medicine Seoul National University Bundang H) Shi Hye Jin (Division of Infectious Disease Department of Internal Medicine Gil Medical Center Gachon University) Hong Shin Hee (Division of Infectious Disease Department of Internal Medicine Gil Medical Center Gachon University) Jun Jae-Bum (Division of Infectious Diseases Department of Internal Medicine Ulsan University Hospital Universit) Hong Kyung-Wook (Department of Internal Medicine Gyeongsang National University Hospital Gyeongsang National Univers) Choi Jae-Phil (Division of Infectious Disease Department of Internal Medicine Seoul Medical Center Seoul Korea.) Kim Jinyeong (Division of Infectious Disease Department of Internal Medicine Hanyang University Guri Hospital Gur) Yang Kyung Sook (Department of Biostatistics Korea University College of Medicine Seoul Korea.) Yoon Young Kyung (Division of Infectious Diseases Department of Internal Medicine Korea University College of Medicin)
저널정보
대한의학회 Journal of Korean Medical Science Journal of Korean Medical Science Vol.37 No.41
발행연도
2022.10
수록면
1 - 12 (12page)
DOI
10.3346/jkms.2022.37.e297

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Background: This study aimed to describe the maternal, obstetrical, and neonatal outcomes in pregnant women with coronavirus disease 2019 (COVID-19) and identify the predictors associated with the severity of COVID-19. Methods: This multicenter observational study included consecutive pregnant women admitted because of COVID-19 confirmed using reverse transcriptase-polymerase chain reaction (RT-PCR) test at 15 hospitals in the Republic of Korea between January 2020 and December 2021. Results: A total of 257 women with COVID-19 and 62 newborns were included in this study. Most of the patients developed this disease during the third trimester. Nine patients (7.4%) developed pregnancy-related complications. All pregnant women received inpatient treatment, of whom 9 (3.5%) required intensive care, but none of them died. The gestational age at COVID-19 diagnosis (odds ratio [OR], 1.096, 95% confidence interval [CI], 1.04–1.15) and parity (OR, 1.703, 95% CI, 1.13–2.57) were identified as significant risk factors of severe diseases. Among women who delivered, 78.5% underwent cesarean section. Preterm birth (38.5%), premature rupture of membranes (7.7%), and miscarriage (4.6%) occurred, but there was no stillbirth or neonatal death. The RT-PCR test of newborns’ amniotic fluid and umbilical cord blood samples was negative for severe acute respiratory syndrome coronavirus 2. Conclusion: At the time of COVID-19 diagnosis, gestational age and parity of pregnant women were the risk factors of disease severity. Vertical transmission of COVID-19 was not observed, and maternal severity did not significantly affect the neonatal prognosis.
#Severe Acute Respiratory Syndrome Coronavirus 2 #Coronavirus Disease 2019 #Pregnancy #Neonate

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