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자료유형
학술저널
저자정보
Nam Jae-Sik (Department of Anesthesiology and Pain Medicine Asan Medical Center University of Ulsan College of M) Chin Ji-Hyun (Department of Anesthesiology and Pain Medicine Asan Medical Center University of Ulsan College of M) Kang Hyun-Uk (Department of Anesthesiology and Pain Medicine Asan Medical Center University of Ulsan College of M) Kim Juyoun (Department of Anesthesiology and Pain Medicine Asan Medical Center University of Ulsan College of M) 정경운 (울산대학교(의대)) Choi In-Cheol (Department of Anesthesiology and Pain Medicine Asan Medical Center University of Ulsan College of M)
저널정보
대한마취통증의학회(구 대한마취과학회) Korean Journal of Anesthesiology Korean Journal of Anesthesiology Vol.75 No.5
발행연도
2022.10
수록면
416 - 426 (11page)
DOI
10.4097/kja.22201

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Background: Left ventricular longitudinal strain is an emerging marker of ventricular systolic function. However, the prognostic value of apical four-chamber longitudinal strain after heart valve surgery in real-world clinical practice is uncertain. The authors investigated whether left ventricular apical four-chamber longitudinal strain measured in real-world practice is helpful for predicting postoperative outcomes in patients undergoing heart valve surgery. Methods: This observational cohort study was conducted in patients who underwent heart valve surgery between January 2014 and December 2018 at a tertiary hospital in South Korea. The exposure of interest was preoperative left ventricular apical four-chamber longitudinal strain. The primary outcome was postoperative all-cause mortality. Results: Among 1,773 study patients (median age, 63 years; female, 45.9%), 132 (7.4%) died during a median follow-up of 27.2 months. Preoperative left ventricular apical four-chamber longitudinal strain was significantly associated with all-cause mortality (adjusted hazard ratio, 0.94 per 1% increment in absolute value; 95% CI [0.90, 0.99], P = 0.022), whereas left ventricular ejection fraction (LVEF) was not significantly associated with all-cause mortality (adjusted hazard ratio: 1.01, 95% CI [0.99, 1.03], P = 0.222). Moreover, combining left ventricular apical four-chamber longitudinal strain to the LVEF and conventional prognostic factors enhance the prognostic model for all-cause mortality (P = 0.022). Conclusions: In patients undergoing heart valve surgery without coronary artery disease, left ventricular apical four-chamber longitudinal strain measured in real-world clinical practice was independently associated with postoperative survival. Left ventricular longitudinal strain measurement may be helpful for outcome prediction after valve surgery.

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