지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2022.4
- 수록면
- 303 - 311 (9page)
- DOI
- https://doi.org/10.3803/EnM.2021.1332
이용수
초록· 키워드
오류제보하기
Background: High-density lipoprotein cholesterol (HDL-C) plays an important role in the reverse cholesterol transport pathwayand prevents atherosclerosis-mediated disease. It has also been suggested that HDL-C may be a protective factor against cancer.
However, an inverse correlation between HDL-C and cancer has not been established, and few studies have explored thyroid cancer.
Methods: The study participants received health checkups provided by the Korean National Health Insurance Service from 2009 to2013 and were followed until 2019. Considering the variability of serum HDL-C level, low HDL-C level was analyzed by groupingbased on four consecutive health checkups. The data analysis was performed using univariate and multivariate Cox proportionalhazard regression models.
Results: A total of 3,134,278 total study participants, thyroid cancer occurred in 16,129. In the crude model, the hazard ratios for theassociation between repeatedly measured low HDL-C levels and thyroid cancer were 1.243, 1.404, 1.486, and 1.680 (P for trend<0.01), respectively, which were significant even after adjusting for age, sex, lifestyle factors, and metabolic diseases. The subgroupanalysis revealed that low HDL-C levels likely had a greater impact on the group of patients with central obesity (P for interaction=0.062), high blood pressure (P for interaction=0.057), impaired fasting glucose (P for interaction=0.051), and hyperlipidemia(P for interaction=0.126).
Conclusion: Repeatedly measured low HDL-C levels can be considered a risk factor for cancer as well as vascular disease. LowHDL-C levels were associated with the risk of thyroid cancer, and this correlation was stronger in a metabolically unhealthy population.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
HDL Subclass Analysis in Predicting Metabolic Syndrome in Koreans With High HDL Cholesterol Levels
Annals of Laboratory Medicine
2020 .01
-
Higher High Density Lipoprotein 2 (HDL2) to Total HDL Cholesterol Ratio Is Associated with a Lower Risk for Incident Hypertension
Diabetes and Metabolism Journal
2019 .01
-
HDL-C and Cardiovascular Risk: You Don't Need to Worry about Extremely High HDL-C Levels
지질·동맥경화학회지
2021 .01
-
Association of High-Density Lipoprotein Cholesterol Phenotypes with the Risk of Cardiovascular Diseases and Mortality: A Cohort Study in Korea
Endocrinology and Metabolism
2022 .04
-
항암치료 받는 악성 뇌종양 환자의 재발여부에 따른 지질프로필 비율의 비교
기초간호자연과학회지
2017 .01
-
Risk assessment of metabolic syndrome in adolescents using the triglyceride/high-density lipoprotein cholesterol ratio and the total cholesterol/high-density lipoprotein cholesterol ratio
Annals of Pediatirc Endocrinology & Metabolism
2019 .01
-
Risk Factors for Thyroid Cancer: A Hospital-Based Case-Control Study in Korean Adults
Cancer Research and Treatment
2017 .01
-
Calibration of High-Density Lipoprotein Cholesterol Values From the Korea National Health and Nutrition Examination Survey Data, 2008 to 2015
Annals of Laboratory Medicine
2017 .01
-
High-Density Lipoprotein, Lecithin: Cholesterol Acyltransferase, and Atherosclerosis
Endocrinology and Metabolism
2016 .01
-
Epigenetic Modifications: Novel Therapeutic Approach for Thyroid Cancer
Endocrinology and Metabolism
2017 .01
-
Associations of Serum Lipid Level with Gastric Cancer Risk, Pathology, and Prognosis
Cancer Research and Treatment
2021 .01
-
Thyroid Cancer Epidemiology in Iran: a Time Trend Study
Asian Pacific journal of cancer prevention : APJCP
2016 .01
-
Present and future of the treatment of thyroid cancer
대한외과학회 학술대회 초록집
2015 .11
-
Novel Associations between Related Proteins and Cellular Effects of High-Density Lipoprotein
Korean Circulation Journal
2020 .01
-
Association between Serum Gamma-Glutamyl Transferase and Thyroid Cancer in an Ultrasonographically Screened Population
International Journal of Thyroidology
2015 .01
-
Thyroid Cancer Surgery
대한외과학회 학술대회 초록집
2022 .11
-
Treatment strategies for thyroid cancer based on Big Data
대한외과학회 학술대회 초록집
2015 .11
-
Changes in High-Density Lipoprotein Cholesterol and Risks of Cardiovascular Events: A Post Hoc Analysis from the PICASSO Trial
대한뇌졸중학회지
2020 .01
-
Survival Comparison of Incidentally Found versus Clinically Detected Thyroid Cancers: An Analysis of a Nationwide Cohort Study
Endocrinology and Metabolism
2023 .02
-
갑상선암의 병기·예후 자동 계산과 수술 후 치료 및 추적 관찰법을 제시하는 프로그램의 개발
대한이비인후-두경부외과학회지
2015 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0